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2 例与狩猎相关的反复发作性呼吸窘迫病例的治疗。

Treatment of recurrent hunting-associated respiratory distress episodes in 2 dogs.

机构信息

Internal Medicine Unit, Centre Hospitalier Vétérinaire Frégis, 43, Av. Aristide Briand, 94110 Arcueil, France.

Diagnosis Imaging Unit, Centre Hospitalier Vétérinaire Frégis, 43, Av. Aristide Briand, 94110 Arcueil, France.

出版信息

J Vet Intern Med. 2023 Nov-Dec;37(6):2514-2519. doi: 10.1111/jvim.16665. Epub 2023 Oct 25.

Abstract

Noncardiogenic pulmonary edema (NCPE) in hunting dogs is an uncommon and poorly described condition for which no preventive treatment is available. Two dogs were presented for recurrent respiratory distress strictly associated with hunting activities. Diagnosis was based on bilateral, symmetrical, interstitial-to-alveolar pattern in the caudodorsal lung fields on thoracic radiographs, exclusion of other causes, and spontaneous clinical and radiographic improvement. Considering that the pathogenesis of exercise-induced NCPE likely involves α- and β-adrenergic overstimulation, treatment with sympathetic blockers was used in both dogs. The first dog no longer showed respiratory signs during hunting activities. However, treatment failed to prevent respiratory distress in the other dog. Based on the large number of red blood cells in the bronchoalveolar lavage fluid of the second dog, exercise-induced pulmonary hemorrhage was suspected, as described in racing horses. The loop diuretic furosemide successfully prevented further hunting-associated respiratory distress episodes in this dog.

摘要

猎犬非心源性肺水肿(NCPE)是一种罕见且描述不佳的疾病,目前尚无预防治疗方法。两只狗因与狩猎活动密切相关的反复发作性呼吸窘迫而就诊。诊断基于胸部 X 射线显示的背侧肺野的双侧、对称、间质性到肺泡模式,排除其他原因,并自发地临床和放射学改善。考虑到运动诱发的 NCPE 的发病机制可能涉及α-和β-肾上腺素能过度刺激,因此对两只狗均使用了交感神经阻滞剂进行治疗。第一只狗在狩猎活动中不再出现呼吸迹象。然而,治疗未能预防另一只狗的呼吸窘迫。基于第二只狗支气管肺泡灌洗液中的大量红细胞,怀疑其患有运动性肺出血,正如赛马中所描述的那样。在这只狗中,噻嗪类利尿剂呋塞米成功地预防了进一步与狩猎相关的呼吸窘迫发作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702a/10658495/d672b600d8a4/JVIM-37-2514-g001.jpg

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