Hadjipavlou Alexander G, Kontakis George M, Gaitanis John N, Katonis Pavlos G, Lander Philip, Crow Wayne N
Department of Orthopaedics-Traumatology, University of Crete, Greece.
Clin Orthop Relat Res. 2003 Jun(411):54-60. doi: 10.1097/01.blo.0000068184.83581.86.
Seventy-one percutaneous transpedicle biopsy specimens were taken from 68 patients with cervical, thoracic, lumbar, or sacral vertebral lesions, with the patients under local anesthesia. Sixty-one procedures were done with fluoroscopic guidance and seven procedures were done with computed tomography guidance. Twenty-one patients were diagnosed as having infectious spondylodiscitis, three had tuberculosis, two had coccidiomycosis, two had brucellosis, one had blastomycosis, one had an echinococcus cyst, six had primary neoplasms, 14 had metastatic neoplasms, five had osseous repair for insufficiency fractures, seven had osteoporotic fractures, and one had Paget's disease of bone. In the four remaining patients, the biopsy initially was negative but it was proven to be false-negative because of faulty biopsy technique. The percutaneous transpedicle approach for biopsy is safe, efficacious, and cost-effective. False-negative results and complications can be avoided when adhering to the technical details of this procedure.
对68例颈椎、胸椎、腰椎或骶椎病变患者在局部麻醉下进行了71次经皮椎弓根活检。61次操作在透视引导下进行，7次操作在计算机断层扫描引导下进行。21例患者被诊断为感染性椎间盘炎，3例为结核病，2例为球孢子菌病，2例为布鲁氏菌病，1例为芽生菌病，1例为棘球蚴囊肿，6例为原发性肿瘤，14例为转移性肿瘤，5例为不全骨折的骨修复，7例为骨质疏松性骨折，1例为佩吉特骨病。其余4例患者活检最初为阴性，但因活检技术有误被证明为假阴性。经皮椎弓根活检方法安全、有效且具有成本效益。遵循该操作的技术细节可避免假阴性结果和并发症。
