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椎体成形术治疗背痛。

Vertebroplasty in the treatment of back pain.

作者信息

Muto Mario, Muto Emanuele, Izzo Roberto, Diano Alvaro Antonio, Lavanga Arcangelo, Di Furia Ugo

机构信息

U. O. di Neuroradiologia, AORN Cardarelli, Naples.

出版信息

Radiol Med. 2005 Mar;109(3):208-19.

Abstract

PURPOSE

The aim of this study is to show the utility of vertebroplasty in the treatment of some types of back pain. Vertebroplasty is a venous embolisation of the vertebral body performed under computed tomography (CT) or fluoroscopy guidance with transpedicular, anterolateral, intercostovertebral or posterolateral approach with acrylic cement.

MATERIALS AND METHODS

We report our experience in 85 patients suffering from low back and thoracic pain and treated with percutaneous vertebroplasty owing to osteoporotic vertebral compression fractures, vertebral haemangiomas or secondary lytic lesions of the spine. Patient selection was performed on the basis of physical examination, magnetic resonance or less frequently, with bone scan. CT has a minor role in selected cases to evaluate the integrity of the posterior wall. We treated 55 patients affected by acute osteoporotic vertebral compression fracture, 10 patients with vertebral haemangioma and 20 patients with metastatic lesions. The patients were placed in the prone position and the procedure was performed under fluoroscopy guidance in 80 patients and under CT guidance in 5 patients affected by metastatic lesions. In no cases was phlebography performed before the treatment. The approach adopted was bilateral in 45 patients and unilateral in the remaining 30 cases. Injection with a low viscosity cement was performed under fluoroscopy guidance with extreme precision in all cases. The amount of cement injected ranged from 4 ml (thoracic level) up to 12 ml (lumbar level).

RESULTS

The results were better for osteoporotic cases (95%) and patients with vertebral haemangioma (90%) than with metastatic lesions (77%), with improvement within 24-72 hours after the treatment. We noted asymptomatic cement leakage in 39 cases but only in 2 cases was there an acute radiculopathy due to epidural cement leakage, which was treated and resolved medically in 1 month. At follow-up no cases were noted of fractures of vertebral bodies adjacent to the treated vertebrae.

DISCUSSION AND CONCLUSIONS

Since the first case of vertebroplasty was used in vertebral haemangioma, the possibility of using this technique in other pathological conditions such as metastatic lesions and osteoporotic compression fractures has been clear. MR has a key role in the selection of patients while bone scan and CT can be useful in selected cases. Absolute controindication is local or systemic infection while relative controindications are epidural extension of the neoplastic lesion, vertebra plana, clinical signs of myelopathy or radiculopathy and coagulation disorders. The results of our study were better in patients treated for osteoporosis or haemangioma than in cancer patients. We consider percutaneous vertebroplasty a valid technique for the treatment of the pain due to osteoporotic compression fractures, vertebral haemangiomas or metastatic lesions.

摘要

目的

本研究旨在展示椎体成形术在治疗某些类型背痛中的效用。椎体成形术是在计算机断层扫描(CT)或荧光透视引导下,采用经椎弓根、前外侧、肋间或后外侧入路,向椎体注入丙烯酸骨水泥进行静脉栓塞。

材料与方法

我们报告了85例因骨质疏松性椎体压缩骨折、椎体血管瘤或脊柱继发性溶骨性病变而接受经皮椎体成形术治疗的腰背痛和胸背痛患者的经验。患者选择基于体格检查、磁共振成像,较少情况下采用骨扫描。在某些选定病例中,CT在评估后壁完整性方面作用较小。我们治疗了55例急性骨质疏松性椎体压缩骨折患者、10例椎体血管瘤患者和20例转移性病变患者。患者取俯卧位,80例患者在荧光透视引导下进行手术,5例转移性病变患者在CT引导下进行手术。所有病例在治疗前均未进行静脉造影。45例患者采用双侧入路,其余30例采用单侧入路。所有病例均在荧光透视引导下极其精确地注射低粘度骨水泥。注入的骨水泥量从4毫升(胸椎水平)到12毫升(腰椎水平)不等。

结果

骨质疏松病例(95%)和椎体血管瘤患者(90%)的治疗效果优于转移性病变患者(77%),治疗后24 - 72小时内症状改善。我们注意到39例无症状性骨水泥渗漏,但只有2例因硬膜外骨水泥渗漏导致急性神经根病,经治疗1个月后病情缓解。随访时未发现治疗椎体相邻椎体骨折病例。

讨论与结论

自从第一例椎体成形术用于治疗椎体血管瘤以来,在转移性病变和骨质疏松性压缩骨折等其他病理状况下使用该技术的可能性已很明确。磁共振成像在患者选择中起关键作用,而骨扫描和CT在某些选定病例中可能有用。绝对禁忌证是局部或全身感染,相对禁忌证是肿瘤病变的硬膜外扩展、扁平椎体、脊髓病或神经根病的临床体征以及凝血障碍。我们的研究结果显示,接受骨质疏松或血管瘤治疗的患者比癌症患者效果更好。我们认为经皮椎体成形术是治疗骨质疏松性压缩骨折、椎体血管瘤或转移性病变所致疼痛的有效技术。

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