进行肾活检的系统性红斑狼疮患者中血栓性血小板减少性紫癜的发生率。
The frequency of thrombotic thrombocytopenic purpura in patients with systemic lupus erythematosus undergoing kidney biopsy.
作者信息
Manadan Augustine M, Harris Charlotte, Schwartz Melvin M, Block Joel A
机构信息
Rush Medical College, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL, USA.
出版信息
J Rheumatol. 2003 Jun;30(6):1227-30.
OBJECTIVE
To characterize the frequency of thrombotic thrombocytopenic purpura (TTP) among patients with systemic lupus erythematosus (SLE) undergoing kidney biopsy.
METHODS
A retrospective review of all renal biopsies of patients with SLE at Rush-Presbyterian-St. Luke's Medical Center was performed for the years 1989 to 2001.
RESULTS
Four cases of clinical and histopathological TTP were identified among the 257 patients with SLE who underwent renal biopsy during the 12 year study period.
CONCLUSION
TTP appears to occur at higher than expected frequency among SLE patients undergoing biopsy for unexplained renal failure.
目的
确定接受肾活检的系统性红斑狼疮（SLE）患者中血栓性血小板减少性紫癜（TTP）的发生频率。
方法
对1989年至2001年在拉什长老会圣卢克医疗中心进行的所有SLE患者肾活检进行回顾性研究。
结果
在12年研究期间接受肾活检的257例SLE患者中，发现4例临床及组织病理学确诊的TTP。
结论
在因不明原因肾衰竭接受活检的SLE患者中，TTP的发生率似乎高于预期。
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