Tashiro Kunio
Department of Neurology, Hokkaido University School of Medicine.
Rinsho Shinkeigaku. 2002 Nov;42(11):1031-9.
The Department of Neurology, Hokkaido University, has been established since 1987, however the bases for neurology had been cultivated through psychiatry and neurosurgery in Hokkaido, especially under the pioneering work by Professor Mitsuo Tsuru. Hokkaido, the northernmost island of Japan, is located between 42 and 46 degrees, and the people have ancestors from various parts of Japan, since this island was reclaimed about 130 years ago. Three major neurological disorders, such as multiple sclerosis(MS), spinocerebellar degeneration(SCD) and Parkinson disease (PD), were discussed on the bases of Hokkaido island. We proved the existence of definite north-south gradient of MS, prevalence rate of 8.6 in Tokachi, Hokkaido, compared with 1-2 in the southern island. SCD, especially hereditary SCD, such as SCA1, SCA2 and SCA14 were reported from Hokkaido. The epidemiological studies of PD showed the prevalence rate of 104.6 at Iwamizawa, Hokkaido in 2000, and we proposed the prevalence rate of PD was close to those of Western countries under the collaborative works with Yonago, Kyoto, and Kagoshima by 2001. Neurology, and its specialization and training programs were also discussed to propose the importance of Neurology in Japan.
北海道大学神经学系自1987年成立以来，然而神经学的基础是在北海道通过精神病学和神经外科培养起来的，特别是在鹤光夫教授的开创性工作之下。北海道是日本最北部的岛屿，位于北纬42度至46度之间，自该岛约130年前开垦以来，这里的人们有着来自日本各地的祖先。基于北海道岛讨论了三种主要的神经系统疾病，如多发性硬化症（MS）、脊髓小脑变性（SCD）和帕金森病（PD）。我们证实了MS存在明确的南北梯度，北海道十胜地区的患病率为8.6，而南部岛屿为1 - 2。北海道报告了SCD，特别是遗传性SCD，如SCA1、SCA2和SCA14。帕金森病的流行病学研究显示，2000年北海道岩见泽的患病率为104.6，到2001年，在与米子、京都和鹿儿岛的合作研究中，我们提出帕金森病的患病率接近西方国家。还讨论了神经学及其专业化和培训计划，以提出神经学在日本的重要性。
