Jordan Lori C., Singer Harvey S.
Johns Hopkins Hospital, Jefferson Building 1-124, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Curr Treat Options Neurol. 2003 Jul;5(4):283-290. doi: 10.1007/s11940-003-0034-8.
Sydenham chorea is an important cause of acquired chorea in childhood. Although the symptoms of chorea frequently resolve spontaneously in a matter of months, abnormal movements can be debilitating when they are present. Neuropsychologic symptoms may antedate the motor abnormality, may be persistent, and often are of great concern. To date, there have been no adequate, double-blind, randomized studies to evaluate the symptomatic treatment of Sydenham chorea. This article will review proposed treatment options and dosing strategies.
西德纳姆舞蹈病是儿童后天性舞蹈病的一个重要病因。尽管舞蹈病症状通常在数月内会自行缓解,但异常运动出现时可能会使人衰弱。神经心理症状可能先于运动异常出现,可能持续存在,且常常令人十分担忧。迄今为止,尚无充分的双盲随机研究来评估西德纳姆舞蹈病的症状性治疗。本文将综述推荐的治疗选择和给药策略。