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富含单不饱和脂肪酸的坚果对高脂血症大鼠血脂的影响

[Effect of nuts enrich in monounsaturated acid on serum lipid of hyperlipidemia rats].

作者信息

Yan Shaofang, Xiao Ying, Wang Junbo, Liang Xuejun

机构信息

Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100083, China.

出版信息

Wei Sheng Yan Jiu. 2003 Mar;32(2):120-2.

PMID:12793000
Abstract

In order to observe the regulatory effect of monounsaturated acid-enriched almond and macadamia nuts on blood lipid-level (TC, TG, HDL-C), the hyperlipidemia Wistar rats were used as the model and a diet containing almond and macadamia at the doses of between 12.5% and 25.0% was given for six weeks. The results showed that the level of the serum TC and TG in each study group was significantly lower than that of high fat chow control group (P < 0.05). There was a significant increase (P < 0.05) in the serum HDL-C level in the high fat chow group with high-dose macadamias compared with that in the high fat chow control group. The findings suggested that nuts enrich in monounsaturated acid could decrease the level of serum TC and TG and macadamias could increased the level of serum HDL-C in the hyperlipidemia rats.

摘要

为观察富含单不饱和脂肪酸的杏仁和澳洲坚果对血脂水平(总胆固醇、甘油三酯、高密度脂蛋白胆固醇)的调节作用,以高脂血症Wistar大鼠为模型,给予含12.5%至25.0%剂量杏仁和澳洲坚果的饲料,持续六周。结果显示,各研究组血清总胆固醇和甘油三酯水平均显著低于高脂饲料对照组(P<0.05)。与高脂饲料对照组相比,高剂量澳洲坚果的高脂饲料组血清高密度脂蛋白胆固醇水平显著升高(P<0.05)。研究结果表明,富含单不饱和脂肪酸的坚果可降低高脂血症大鼠血清总胆固醇和甘油三酯水平,澳洲坚果可升高其血清高密度脂蛋白胆固醇水平。

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