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先天性心脏病患儿心脏直视手术后的早期术后心律失常。

Early postoperative arrhythmias after open-heart procedures in children with congenital heart disease.

作者信息

Pfammatter Jean-Pierre, Bachmann Denis C.G., Wagner Bendicht P., Pavlovic Mladen, Berdat Pascal, Carrel Thierry, Pfenninger Jürg

机构信息

Department of Pediatric Cardiology (Drs. Pfammatter and Pavlovic), the Pediatric Intensive Care Unit (Drs. Bachmann, Wagner, and Pfenninger), and the Department of Cardiovascular Surgery (Drs. Berdat and Carrel), University Hospital Berne, Switzerland. E-mail:

出版信息

Pediatr Crit Care Med. 2001 Jul;2(3):217-222. doi: 10.1097/00130478-200107000-00005.

Abstract

OBJECTIVE

Evaluation of occurrence, clinical course, necessity of treatment, and outcome of early postoperative cardiac arrhythmias after open-heart surgery. DESIGN: Prospective study. SETTING: Tertiary pediatric intensive care and pediatric cardiology unit. PATIENTS: All consecutive pediatric patients undergoing cardiac surgery on cardiopulmonary bypass were studied for the occurrence of cardiac arrhythmias during the whole perioperative hospital stay. Measurements: All patients had continuous electrocardiographic monitoring (with memory function) during the whole intensive care stay. A 24-hr Holter recording was done thereafter in patients with arrhythmias. RESULTS: Of 310 patients studied, 83 (27%) had postoperative arrhythmias. The occurrence rate was not different whether surgical access was by atriotomy or ventriculotomy (26% vs. 28%, respectively). Infants (39%) and cyanotic patients (36%) had a higher occurrence rate of arrhythmias (p <.05). Arrhythmias were more common after prolonged cardiopulmonary bypass time and with higher postoperative maximum troponin serum levels. In addition, patients with hemodynamically significant residual findings after correction had an increased occurrence rate of arrhythmias (18 of 43; 42%; p <.01). Of the 83 children with arrhythmias, 53 (64%) required specific antiarrhythmic treatment. The use of antiarrhythmic drugs was required in only 7 of these patients. Only one patient (1.2% of patients with arrhythmias) died from arrhythmia. No major complications resulting from arrhythmias occurred during the postoperative clinical course in the other patients. CONCLUSIONS: Although they occur frequently, postoperative arrhythmias after open-heart procedures in children are associated with low morbidity and mortality.

摘要

目的

评估心脏直视手术后早期心律失常的发生率、临床过程、治疗必要性及预后。

设计

前瞻性研究。

地点

三级儿科重症监护和儿科心脏病科病房。

患者

对所有接受体外循环心脏手术的连续儿科患者在整个围手术期住院期间心律失常的发生情况进行研究。

测量

所有患者在重症监护期间均进行连续心电图监测(具有记忆功能)。此后,对有心律失常的患者进行24小时动态心电图记录。

结果

在研究的310例患者中,83例(27%)术后出现心律失常。无论手术入路是心房切开术还是心室切开术,发生率无差异(分别为26%和28%)。婴儿(39%)和青紫型患者(36%)心律失常发生率较高(p<.05)。体外循环时间延长和术后肌钙蛋白血清最高水平较高时,心律失常更常见。此外,矫正后有血流动力学显著残余病变的患者心律失常发生率增加(43例中的18例;42%;p<.01)。在83例有心律失常的儿童中,53例(64%)需要特定的抗心律失常治疗。其中仅7例患者需要使用抗心律失常药物。仅1例患者(占心律失常患者的1.2%)死于心律失常。其他患者术后临床过程中未发生因心律失常导致的重大并发症。

结论

尽管儿童心脏直视手术后心律失常频繁发生,但发病率和死亡率较低。

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