Rekawek Joanna, Kansy Andrzej, Miszczak-Knecht Maria, Manowska Małgorzata, Bieganowska Katarzyna, Brzezinska-Paszke Monika, Szymaniak Elzbieta, Turska-Kmieć Anna, Maruszewski Przemysław, Burczyński Piotr, Kawalec Wanda
Department of Cardiology, Children's Memorial Health Institute, Warsaw, Poland.
J Thorac Cardiovasc Surg. 2007 Apr;133(4):900-4. doi: 10.1016/j.jtcvs.2006.12.011.
Early postoperative arrhythmias are a recognized complication of pediatric cardiac surgery.
Diagnosis and treatment of early postoperative arrhythmias were prospectively analyzed in 402 consecutive patients aged 1 day to 18 years (mean 29.5 months) who underwent operation between January and December 2005 at our institute. All children were admitted to the intensive care unit, and continuous electrocardiogram monitoring was performed. Risk factors, such as age, weight, Aristotle Basic Score, cardiopulmonary bypass time, aortic crossclamp time, and use of deep hypothermia and circulatory arrest, were compared. Statistical analysis using the Student t test, Mann-Whitney U test, or Fisher exact test was performed. Multivariate stepwise logistic regression was used to assess the risk factors of postoperative arrhythmias.
Arrhythmias occurred in 57 of 402 patients (14.2%). The most common types of arrhythmia were junctional ectopic tachycardia (21), supraventricular tachycardia (15), and arteriovenous block (6). Risk factors for arrhythmias, such as lower age (P = .0041*), lower body weight (P = .000001*), higher Aristotle Basic Score (P = .000001*), longer cardiopulmonary bypass time (P = .000001*), aortic crossclamp time (P = .000001*), and use of deep hypothermia and circulatory arrest (P = .0188*), were identified in a univariate analysis. In the multivariate stepwise logistic regression, only higher Aristotle Basic Score was statistically significant (P = .000003*) compared with weight (P = .62) and age (P = .40); in the cardiopulmonary bypass group, only longer aortic crossclamp time was statistically significant (P = .007*).
Lower age, lower body weight, higher Aristotle Basic Score, longer cardiopulmonary bypass time, aortic crossclamp time, and use of deep hypothermia and circulatory arrest are the risk factors for postoperative arrhythmias. Junctional ectopic tachycardia and supraventricular tachycardia were the most common postoperative arrhythmias.
术后早期心律失常是小儿心脏手术公认的并发症。
对2005年1月至12月在我院接受手术的402例年龄1天至18岁(平均29.5个月)的连续患者进行术后早期心律失常的诊断和治疗的前瞻性分析。所有患儿均入住重症监护病房,并进行连续心电图监测。比较年龄、体重、亚里士多德基础评分、体外循环时间、主动脉阻断时间以及深低温停循环的使用等危险因素。采用学生t检验、曼-惠特尼U检验或费舍尔精确检验进行统计学分析。使用多因素逐步逻辑回归评估术后心律失常的危险因素。
402例患者中有57例(14.2%)发生心律失常。最常见的心律失常类型为交界性异位性心动过速(21例)、室上性心动过速(15例)和动静脉阻滞(6例)。单因素分析确定了心律失常的危险因素,如年龄较小(P = 0.0041*)、体重较低(P = 0.000001*)、亚里士多德基础评分较高(P = 0.000001*)、体外循环时间较长(P = 0.000001*)、主动脉阻断时间(P = 0.000001*)以及深低温停循环的使用(P = 0.0188*)。在多因素逐步逻辑回归中,与体重(P = 0.62)和年龄(P = 0.40)相比,只有较高的亚里士多德基础评分具有统计学意义(P = 0.000003*);在体外循环组中,只有较长的主动脉阻断时间具有统计学意义(P = 0.007*)。
年龄较小、体重较低、亚里士多德基础评分较高、体外循环时间较长、主动脉阻断时间以及深低温停循环的使用是术后心律失常的危险因素。交界性异位性心动过速和室上性心动过速是最常见的术后心律失常。