Toros Fevziye, Tot Senal, Avci Ayşe
Mersin U Tip Fak, Psikiyatri AD.
Turk Psikiyatri Derg. 2002 Autumn;13(3):187-95.
The aim of this study was to evaluate the sociodemographic and clinical features of children and adolescents with Tourette Disorder (TD) according to DSM-IV who are applied to our outpatient clinic and to determine clinical significance of relationship between the sociodemographic features and the severity of vocal, motor tics, and also to determine frequency of comorbid conditions and diagnosis according to DSM-IV.
Twenty eight children and adolescents (23 boys, 5 girls) were included in this study. Sociodemographic features of cases were recorded and Beck Children Depression Inventory (CDI), Maudsley Obsessive Compulsive Questionnaire (MOCQ), Goetz Tics Evaluation Scale were administered to all children. Clinical features of TD and the comorbid diagnosis were assessed in detail through psychiatric interview according to DSM-IV.
The mean age of the cases at the time of referral was 124 +/- 32 months. Twenty one of the cases (75%) had obsessive compulsive disorder, 4 of them (14.2%) had attention deficit hyperactivity disorder (ADHD), 4 of them (14.2%) had major depression as a comorbid disorder. The most common motor tic was eye blinking and vocal tic was throat cleaning. Coprolali was present in 32.1% of the cases was found to appear in older children. Besides, no significant causal relationship between prenatal, natal, and postnatal conditions of the cases and TD.
The results of the study suggest that there are several common pathologies in the etiology of TD, OCD, ADHD because of the high comorbidity present between these disorders.
本研究旨在评估前来我院门诊就诊的符合《精神疾病诊断与统计手册第四版》(DSM-IV)标准的抽动秽语障碍(TD)儿童及青少年的社会人口统计学和临床特征,确定社会人口统计学特征与发声、运动抽动严重程度之间关系的临床意义,并根据DSM-IV确定共病情况的频率及诊断。
本研究纳入了28名儿童及青少年(23名男孩,5名女孩)。记录病例的社会人口统计学特征,并对所有儿童进行贝克儿童抑郁量表(CDI)、莫兹利强迫症问卷(MOCQ)、戈茨抽动评估量表测试。根据DSM-IV通过精神科访谈详细评估TD的临床特征及共病诊断。
转诊时病例的平均年龄为124±32个月。21例(75%)患有强迫症,4例(14.2%)患有注意力缺陷多动障碍(ADHD),4例(14.2%)患有重度抑郁症作为共病。最常见的运动抽动是眨眼,发声抽动是清嗓。秽语症在32.1%的病例中出现,且多见于年龄较大的儿童。此外,病例的产前、产时及产后情况与TD之间无显著因果关系。
研究结果表明,由于TD、强迫症、ADHD之间存在较高的共病率,这些疾病在病因上存在几种共同的病理机制。