Geisler J P, Gates R W, Shirrell W, Parker S M, Maloney C D, Wiemann M C, Geisler H E
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, St. Vincent Hospital and Health Care Center, Indianapolis, Indiana 46260, USA.
Int J Gynecol Cancer. 1997 Jan;7(1):84-7. doi: 10.1046/j.1525-1438.1997.00405.x.
Extramammary Paget's disease of the lower female genito-urinary system is an uncommon neoplasm with a high rate of recurrence. A 52-year-old white female with a history of extramammary Paget's disease, originally excised in 1985 by skinning vulvectomy and who had multiple recurrences, including two in a vaginal graft and with extension to the urethra and the uterine cervix, in 1992 underwent an anterior pelvic exenteration for control of the disease process. Standard surgical management for extramammary Paget's disease without invasion or without an underlying adenocarcinoma is simple or skinning vulvectomy. However, because the disease commonly recurs, diffuse involvement may require more extensive surgery including pelvic exenteration in extraordinary cases.
女性下泌尿生殖系统的乳房外佩吉特病是一种罕见的肿瘤，复发率很高。一名52岁的白人女性，有乳房外佩吉特病病史，最初于1985年行外阴皮肤切除术，多次复发，包括1992年在阴道移植物中有两次复发，并蔓延至尿道和子宫颈，为控制病情接受了前盆腔脏器清除术。对于无浸润或无潜在腺癌的乳房外佩吉特病，标准的手术治疗是单纯外阴切除术或外阴皮肤切除术。然而，由于该病常复发，弥漫性受累可能需要更广泛的手术，在特殊情况下包括盆腔脏器清除术。
