Lu R M, Dawson A K
Telectronics Pacing Systems, Englewood, CO 80112.
Pacing Clin Electrophysiol. 1992 Nov;15(11 Pt 2):1996-9. doi: 10.1111/j.1540-8159.1992.tb03009.x.
Previous studies have shown that the paced depolarization integral (PDI) data recorded in unipolar configuration could potentially improve the specificity of tachyarrhythmia classification in an implantable cardioverter defibrillator (ICD). However, the defibrillation protection would be compromised if the ICD case were used as an indifferent electrode. Since transvenous defibrillation leads are being investigated to be used with ICDs, this study determined if reliable PDI data could be obtained using the braided endocardial defibrillation lead (BEDL). The results demonstrated that comparable PDI values and PDI changes with epinephrine induced sinus tachycardia were obtained with all three tested sensing configurations: conventional unipolar, tip electrode to right ventricular defibrillation electrode, and tip electrode to superior vena cava defibrillation electrode. Therefore, the BEDL can be used to measure PDI data, which possibly may improve tachyarrhythmia classification in an ICD, without compromising its defibrillation protection.
先前的研究表明，单极配置下记录的起搏去极化积分（PDI）数据可能会提高植入式心脏复律除颤器（ICD）中快速性心律失常分类的特异性。然而，如果将ICD外壳用作无关电极，除颤保护功能将会受损。由于正在研究经静脉除颤导线与ICD配合使用，本研究确定了使用编织心内膜除颤导线（BEDL）是否能够获得可靠的PDI数据。结果表明，在所有三种测试的感知配置下，即传统单极、尖端电极至右心室除颤电极以及尖端电极至上腔静脉除颤电极，均获得了与肾上腺素诱发的窦性心动过速相当的PDI值和PDI变化。因此，BEDL可用于测量PDI数据，这可能会改善ICD中的快速性心律失常分类，而不会损害其除颤保护功能。
