Wooding S
Department of Anthropology, University of Utah, 270 South 1400 East, Salt Lake City, UT 84112-0060, USA.
Infect Genet Evol. 2001 Jul;1(1):3-12. doi: 10.1016/s1567-1348(01)00002-8.
Information about similarities and differences in the demographic history of host and parasite populations is potentially useful for making inferences about a variety of evolutionary processes. However, it is difficult to observe the historical demographic properties of natural populations directly. Here, the extent of demographic similarity in a host and its parasite was examined indirectly by inferring long-term population history from patterns of genetic variation. Nucleotide sequence diversity in human and JC virus (JCV) DNA is consistent with a long-term demographic connection between the two species: both show evidence of large-scale population expansion. However, genetic data also suggest that the two species have different patterns of population substructuring. These similarities and differences have implications for adaptive evolution in JCV that are not evident when the two species are considered separately.
宿主和寄生虫种群在人口统计学历史上的异同信息，对于推断各种进化过程可能是有用的。然而，直接观察自然种群的历史人口统计学特征是困难的。在这里，通过从遗传变异模式推断长期种群历史，间接研究了宿主及其寄生虫在人口统计学上的相似程度。人类和JC病毒（JCV）DNA中的核苷酸序列多样性与这两个物种之间的长期人口统计学联系相一致：两者都显示出大规模种群扩张的证据。然而，遗传数据也表明这两个物种具有不同的种群亚结构模式。这些异同对于JCV的适应性进化具有重要意义，而当分别考虑这两个物种时这些意义并不明显。
