Donabedian H
Departments of Internal Medicine, Microbiology and Immunology, Division of Infectious Diseases, Medical College of Ohio, Toledo, OH 43614, USA.
J Infect. 2003 May;46(4):207-14. doi: 10.1053/jinf.2002.1120.
Quorum sensing allows bacteria to detect the density of their own species and alter their metabolism to take advantage of this density. Quorum sensing is used by a wide variety of bacteria including human pathogens. Quorum sensing genes are important for the pathogenic potential of Pseudomonas aeruginosa and Staphylococcus aureus, as well as other invasive bacteria. An understanding of quorum sensing may lead to new therapeutic strategies.
群体感应使细菌能够检测自身物种的密度，并改变其新陈代谢以利用这种密度。包括人类病原体在内的多种细菌都利用群体感应。群体感应基因对于铜绿假单胞菌、金黄色葡萄球菌以及其他侵袭性细菌的致病潜力至关重要。对群体感应的理解可能会带来新的治疗策略。
