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Evaluation of anti-hsp70 antibody screening in sudden deafness.

作者信息

Samuelsson Anna-Karin, Hydén Dag, Roberg Magnus, Skogh Thomas

机构信息

Division of Rheumatology, Department of Molecular and Clinical Medicine, Faculty of Health Sciences, Linköping University Hospital, Linköping, Sweden.

出版信息

Ear Hear. 2003 Jun;24(3):233-5. doi: 10.1097/01.AUD.0000069230.36940.AC.

DOI:10.1097/01.AUD.0000069230.36940.AC
PMID:12799545
Abstract

OBJECTIVE

To assess the diagnostic utility of anti-hsp70 antibody screening in sudden deafness.

DESIGNS

era from 27 patients with sudden deafness and 100 healthy blood donors were analyzed by Western blotting (WB) for the presence of antibodies against 68 kD heat shock protein (anti-hsp70).

RESULTS

19% of the patient sera and 14% of the control sera turned out positive, which was not significantly different.

CONCLUSIONS

The anti-hsp70 WB test lacks clinical utility for diagnostic screening in patients with sudden deafness.

摘要

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