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反社会人格障碍中的执行与非执行神经心理功能

Executive and nonexecutive neuropsychological functioning in antisocial personality disorder.

作者信息

Crowell Timothy A, Kieffer Kevin M, Kugeares Susana, Vanderploeg Rodney D

机构信息

Department of Psychiatry and Behavioral Medicine, University of South Florida, Tampa, FL, USA.

出版信息

Cogn Behav Neurol. 2003 Jun;16(2):100-9. doi: 10.1097/00146965-200306000-00003.

Abstract

OBJECTIVE

To examine the relationships between antisocial personality disorder and executive abilities as well as antisocial personality disorder with other domains of cognitive functioning.

BACKGROUND

Previous research has suggested that antisocial personality disorder is associated with impaired executive functioning. However, methodological limitations of past research have resulted in inconsistent findings.

METHODS

Executive functioning and other cognitive abilities were compared in four demographically matched groups of middle-aged community dwelling male veterans (N = 336). The groups were: (A). those with active antisocial personality disorder psychopathology; (B). those with a lifetime prevalence of antisocial personality disorder but inactive antisocial personality disorder psychopathology; (C). a nonantisocial personality disorder psychiatrically matched control group; and (D). a normal control group.

RESULTS

Multivariate analysis of variance revealed that the four groups were not statistically significantly different on measures of executive functioning or other cognitive abilities.

CONCLUSIONS

Those with antisocial personality disorder perform at comparable levels to psychiatric and normal controls with respect to executive functioning and other domains of cognitive ability (i.e., language, memory, visuospatial, and motor abilities). An incidental finding was that, over time, the antisocial personality disorder groups improved more than control groups on a measure of general intellectual aptitude.

摘要

目的

研究反社会人格障碍与执行能力之间的关系,以及反社会人格障碍与认知功能其他领域之间的关系。

背景

先前的研究表明,反社会人格障碍与执行功能受损有关。然而,过去研究的方法局限性导致了结果不一致。

方法

在四组人口统计学特征匹配的中年社区男性退伍军人(N = 336)中比较执行功能和其他认知能力。这四组分别为:(A). 患有活跃反社会人格障碍精神病理学症状的人;(B). 有反社会人格障碍终生患病率但无活跃反社会人格障碍精神病理学症状的人;(C). 非反社会人格障碍的精神疾病匹配对照组;以及(D). 正常对照组。

结果

多变量方差分析显示,四组在执行功能或其他认知能力测量上没有统计学上的显著差异。

结论

在执行功能和认知能力的其他领域(即语言、记忆、视觉空间和运动能力)方面,患有反社会人格障碍的人与精神疾病对照组和正常对照组的表现相当。一个偶然的发现是,随着时间的推移,在一般智力能力测量方面,反社会人格障碍组比对照组改善得更多。

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