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胰腺实性假乳头状瘤

Solid pseudopapillary tumour of the pancreas.

作者信息

Ng Kheng Hong, Tan Puay Hoon, Thng Choon Hua, Ooi London Lucien

机构信息

Department of General Surgery, Singapore General Hospital, Singapore.

出版信息

ANZ J Surg. 2003 Jun;73(6):410-5. doi: 10.1046/j.1445-2197.2003.t01-1-02634.x.

DOI:10.1046/j.1445-2197.2003.t01-1-02634.x
PMID:12801340
Abstract

BACKGROUND

Solid pseudopapillary tumour of the pancreas is a rare pancreatic tumour that occurs predominantly in women, with very few cases reported in men. This is a tumour with low malignancy potential and surgical resection usually results in cure.

METHODS

A retrospective review of our experience with solid pseudopapillary tumours between April 1992 and December 2000 was undertaken.

RESULTS

Six patients were identified including one male patient. The median age was 30 years, with four patients presenting with abdominal pain and discomfort and two patients presenting with palpable abdominal masses. The mean tumour diameter was 10.2 cm and the lesions were found mainly in the body and tail of the pancreas. Only one patient had tumour at the pancreatic head. One patient had a locally invasive disease and another had peritoneal spread. None of the patients received adjuvant therapy. The mean follow up was 3.8 years (range: 1.5-10.0) and all patients were free of recurrence to date.

CONCLUSION

SPT is a rare tumour with an unclear origin that has a distinct histology and presentation. Although preoperative diagnosis is difficult by computed tomography, magnetic resonance imaging may potentially improve this situation. In general, this is a tumour of very low malignant potential and long-term survival is excellent after resection of the tumour.

摘要

背景

胰腺实性假乳头状瘤是一种罕见的胰腺肿瘤,主要发生于女性,男性病例报道极少。这是一种恶性潜能较低的肿瘤,手术切除通常可治愈。

方法

对1992年4月至2000年12月间我们诊治胰腺实性假乳头状瘤的经验进行回顾性分析。

结果

共确定6例患者,其中1例男性患者。中位年龄为30岁,4例患者表现为腹痛和不适,2例患者表现为可触及的腹部肿块。肿瘤平均直径为10.2 cm,病变主要位于胰腺体尾部,仅1例患者肿瘤位于胰头。1例患者有局部浸润性病变,另1例有腹膜播散。所有患者均未接受辅助治疗。平均随访3.8年(范围:1.5 - 10.0年),迄今为止所有患者均无复发。

结论

胰腺实性假乳头状瘤是一种起源不明的罕见肿瘤,具有独特的组织学特征和临床表现。尽管通过计算机断层扫描术前诊断困难,但磁共振成像可能会改善这种情况。总体而言,这是一种恶性潜能极低的肿瘤,肿瘤切除后长期生存率良好。

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