Ultrastructural characteristics of cell populations in the gastric and duodenal mucosa during psoriasis.

In biopsy specimens of the gastric and duodenal mucosa from patients with psoriasis we revealed severe degenerative and dystrophic changes in cells of the surface and glandular epithelium with destruction of functionally important cytoplasmic organelles. The stroma of the gastric mucosa was characterized by hyperplasia of the lymphoid tissue, formation of numerous lymphoid follicles, and destruction of the endothelium in microvessels. These changes are interpreted as the syndrome of regenerative and plastic insufficiency.