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Functional changes in the ageing kidney: is there a role for asymmetric dimethylarginine?

作者信息

Kielstein Jan T, Bode-Böger Stefanie M, Haller Hermann, Fliser Danilo

机构信息

Department of Internal Medicine, Medical School Hannover, Germany.

出版信息

Nephrol Dial Transplant. 2003 Jul;18(7):1245-8. doi: 10.1093/ndt/gfg183.

DOI:10.1093/ndt/gfg183
PMID:12808155
Abstract
摘要

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Functional changes in the ageing kidney: is there a role for asymmetric dimethylarginine?衰老肾脏的功能变化:不对称二甲基精氨酸是否起作用?
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Asymmetric dimethylarginine (ADMA) is a novel emerging risk factor for cardiovascular disease and the development of renal injury in chronic kidney disease.不对称二甲基精氨酸(ADMA)是心血管疾病和慢性肾脏病肾损伤发生发展过程中一种新出现的危险因素。
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引用本文的文献

1
Long-term dietary restriction up-regulates activity and expression of renal arginase II in aging mice.长期饮食限制上调衰老小鼠肾脏中精氨酸酶II的活性和表达。
J Biosci. 2017 Jun;42(2):275-283. doi: 10.1007/s12038-017-9683-8.
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The implications of anatomical and functional changes of the aging kidney: with an emphasis on the glomeruli.衰老肾脏的解剖和功能变化的意义:重点介绍肾小球。
Kidney Int. 2012 Aug;82(3):270-7. doi: 10.1038/ki.2012.65. Epub 2012 Mar 21.