Niculescu I T, Zilişteanu E, Creţescu L, Oprescu E
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1975 Jul-Sep;20(3):129-35.
The present paper deals with the conditions that influenza vaccines must comply with, their efficiency in terms of the route of administration, the major antigenic changes of influenza viruses, that has to be known from beforehand, a basic problem for the efficient control of a pandemic. Vaccination must have in view reduction of the mortality and morbidity rate, a major criterion in establishing a programme for the prevention of influenza by vaccination.
本文论述了流感疫苗必须符合的条件、其在给药途径方面的有效性、流感病毒的主要抗原变化(这必须预先知晓,是有效控制大流行的一个基本问题)。疫苗接种必须着眼于降低死亡率和发病率,这是制定流感疫苗接种预防计划的一个主要标准。