Busuioc C, Ionescu V, Tisu A, Stoicescu A, Guguianu E, Bordeianu P, Bordeianu V
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1975 Jul-Sep;20(3):153-63.
The present paper reports on the results of a complex epidemiologic survey of the epidemiologic potential of influenza in Bucharest in 1974, conducted on the basis of a complete, unitary methodology including; (a) Dynamic survey of the morbidity and mortality from influenza, with statistical-mathematical processing of the data per age group and total population; (b) Monthly sero-epidemiologic survey of the antiinfluenza immunologic profile of the population, determined in lots of 540 sera (annual total 7020 serum samples), with statistical-mathematical processing of the serograms; (c) Serodynamic determinations of 67 paired serum smaples collected from patients presenting influenza syndromes during ascension of the epidemic morbidity from influenza; (d) Complex epidemiologic surveys in representative influenza foci in children, adolescent and adult communities. Based upon the result obtained the authors discuss the evolutive particularities of the epidemiologic process in Bucharest, particularly during the epidemic ascension of the first trimester of 1974, caused by the intensified circulation of influenza virus type B. The orientative value of certain elements for the epidemiologic prognosis is emphasized, such as: the immunologic profile of the population per age group with regard to the circulating influenza virus strains (autochtonous or imported strains), active control of the incidence of influenza in communities (technical schools etc.) or enterprises with a large number of employees, laboratory etiologic determinations in cases of a clinical diagnosis of influenza in a preepidemic season. The authors' ten years experience in the active survey of the active epidemiologic potential of influenza in the town of Bucharest shows that the methodology applied was efficient both for scientific assessing of the epidemiologic situation and for an orientation in the choice of preventive and control measures.
本文报道了1974年在布加勒斯特开展的一项关于流感流行潜力的综合流行病学调查结果，该调查基于一套完整、统一的方法进行，包括：(a) 对流感发病率和死亡率进行动态调查，并按年龄组和总人口对数据进行统计数学处理；(b) 每月对人群的抗流感免疫状况进行血清流行病学调查，每次检测540份血清样本（全年共7020份血清样本），并对血清图谱进行统计数学处理；(c) 对流感流行发病率上升期间出现流感综合征的患者采集的67对血清样本进行血清动力学测定；(d) 在儿童、青少年和成人社区的代表性流感疫源地进行综合流行病学调查。根据所得结果，作者讨论了布加勒斯特流行病学过程的演变特点，特别是在1974年第一季度流感流行发病率上升期间，这是由B型流感病毒传播加剧所致。强调了某些因素对流行病学预后的指导价值，如：各年龄组人群针对流行的流感病毒株（本地株或输入株）的免疫状况、对社区（技术学校等）或员工众多的企业中流感发病率的积极控制、在流行季节前对临床诊断为流感的病例进行实验室病因学测定。作者在布加勒斯特市积极调查流感实际流行潜力方面的十年经验表明，所采用的方法对于科学评估流行病学状况以及指导预防和控制措施的选择都是有效的。
