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[使用KMFTR模块化肿瘤内置假体系统治疗下肢骨转移瘤]

[Therapy of bone metastases of the lower extremity with the KMFTR modular tumor endoprosthesis system].

作者信息

Helwig U, Ritschl P, Kotz R

机构信息

Orthopädische Universitätsklinik Wien.

出版信息

Chirurg. 1992 Nov;63(11):938-43.

PMID:1281065
Abstract

During the years 1975 through 1989, 189 patients have been operated because of metastases within bones of the lower extremity. Thereof, 34 patients received an endoprosthesis of the KMFTR (Kotz Modular Femur-Tibia reconstruction system) type. In detail, the following reconstruction elements had been used: proximal femur (n = 20), distal femur (n = 7), complete femur (n = 2), proximal tibia (n = 5). At the time of follow-up examination 30 patients had died. Mean survival time after resection of metastases was 18.6 months (range 8-44 months). According to histologic judgement, in 23 cases wide or marginal resections had been performed whereas 11 patients had been operated intralesionally. In no case local recurrence as relevant to therapy was observed. At the same time-point, survival periods after detection of secondary manifestations of the malignant diseases within the remaining 4 patients were 29, 61, 73 and 125 months, respectively. The following complications were observed: luxation of the prosthesis (n = 6), transient paresis of the peroneus (n = 3), deep vein thrombosis (n = 2), pulmonary infarction (n = 1), wound healing disturbances (n = 2) and hematoma (n = 3).

摘要

在1975年至1989年期间,189例患者因下肢骨转移而接受手术。其中,34例患者接受了KMFTR(科茨模块化股骨 - 胫骨重建系统)类型的内置假体。具体而言,使用了以下重建元件:股骨近端(n = 20)、股骨远端(n = 7)、全股骨(n = 2)、胫骨近端(n = 5)。在随访检查时,30例患者已死亡。转移灶切除后的平均生存时间为18.6个月(范围8 - 44个月)。根据组织学判断,23例患者进行了广泛或边缘切除,而11例患者进行了病灶内手术。未观察到与治疗相关的局部复发情况。在同一时间点,其余4例患者恶性疾病继发表现出现后的生存期分别为29、61、73和125个月。观察到以下并发症:假体脱位(n = 6)、腓骨短暂性麻痹(n = 3)、深静脉血栓形成(n = 2)、肺梗死(n = 1)、伤口愈合障碍(n = 2)和血肿(n = 3)。

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