Doria C, De Santis V, Falcone G, Proietti L, De Santis E
Orthopaedic Department, University of Sassari, Sassari, Italy.
Int Orthop. 2003;27(5):272-7. doi: 10.1007/s00264-003-0474-5. Epub 2003 Jun 17.
Sixteen 2- to 3-year-old sheep were submitted to a hemiarthroplasty of the hip joint with a specially designed femoral component. The proximal two thirds of the stem had a circumferential, plasma-sprayed, porous coating with hydroxyapatite. The animals where killed a 15, 30, 60, 90, 120, 180, 200, 270, 360, and 540 days after surgery. Femurs were submitted to plain radiographs, computerised tomography (CT) scan, and dual energy X-ray absorptiometry (DEXA). Cross-sections were obtained at four different levels and studied using scanning electron microscopy. In the coated portion of the stem, apposition of woven immature bone was evident at 15-30 days and mature lamellar bone by 30 days. With time, the gap between the endosteum and the coated surface was filled by bridges of lamellar bone with a marked trabecular orientation. In the distal uncoated portion of the stem, the implant was initially surrounded by fibrous tissue that, with time, transformed into lamellar bone.
16只2至3岁的绵羊接受了使用特殊设计的股骨部件进行的髋关节半关节成形术。柄的近端三分之二有一个带有羟基磷灰石的圆周等离子喷涂多孔涂层。在手术后15、30、60、90、120、180、200、270、360和540天处死这些动物。对股骨进行X线平片、计算机断层扫描（CT）和双能X线吸收法（DEXA）检查。在四个不同水平获取横截面并使用扫描电子显微镜进行研究。在柄的涂层部分，术后15至30天可见编织状未成熟骨附着，到30天时可见成熟板层骨。随着时间的推移，骨内膜与涂层表面之间的间隙被具有明显小梁方向的板层骨桥填充。在柄的远端未涂层部分，植入物最初被纤维组织包围，随着时间的推移，纤维组织转变为板层骨。
