耐受性：对小鼠和人类而言。
Tolerance: of mice and men.
作者信息
Sachs David H
机构信息
Transplantation Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts 02129, USA.
出版信息
J Clin Invest. 2003 Jun;111(12):1819-21. doi: 10.1172/JCI18926.
Abstract
Little is known about the effect of an individual's immune history on his or her response to an allogeneic tissue transplant. An important study now reveals that individuals harboring virally-induced memory T cells that are cross reactive with donor alloantigen are resistant to conventional strategies designed to induce transplant tolerance.
摘要
关于个体的免疫史对其同种异体组织移植反应的影响，目前所知甚少。一项重要研究现在表明，携带与供体同种异体抗原发生交叉反应的病毒诱导记忆T细胞的个体，对旨在诱导移植耐受的传统策略具有抗性。
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The UNOS Scientific Renal Transplant Registry.器官共享联合网络科学肾脏移植登记处。
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