Srinivasan R, Singh Megha
Biomedical Engineering Division, Indian Institute of Technology. Madras, Chennai 600036, India.
IEEE Trans Biomed Eng. 2003 Jun;50(6):724-30. doi: 10.1109/TBME.2003.812188.
Surface backscattering profiles from a human forearm and transmission profiles through a human thumb, of red and near-infrared lasers, were determined. For the preparation of tissue-equivalent phantoms, white paraffin wax mixed with various wax color pigments were used. The surface reflectance profiles of a human forearm were matched with that of the phantom by mixing color pigments in various proportions. The reconstructed surface reflectance image of the phantom prepared by this procedure was similar to that of the human forearm. The transmission tomogram of the human thumb was obtained in fan-beam configuration by a near-infrared laser tomography system. Based on the horizontal scan of this tomogram, a two-layered phantom was made. The color composition of the phantom was so adjusted that its horizontal scan was matched with that of the thumb tomogram. The phantoms of complex tissues, prepared by this procedure, could be used for evaluation and calibration of new optical diagnostic imaging techniques.
测定了红色和近红外激光在人体前臂的表面背向散射曲线以及透过人体拇指的透射曲线。为制备组织等效体模，使用了混合有各种蜡色颜料的白色石蜡。通过以不同比例混合色颜料，使人体前臂的表面反射率曲线与体模的相匹配。通过此程序制备的体模的重建表面反射率图像与人体前臂的相似。通过近红外激光断层扫描系统以扇形束配置获得了人体拇指的透射断层图像。基于该断层图像的水平扫描，制作了一个双层体模。调整体模的颜色组成，使其水平扫描与拇指断层图像的相匹配。通过此程序制备的复杂组织体模可用于新光学诊断成像技术的评估和校准。
