Hyberts Sven G, Wagner Gerhard
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, MA 02115, USA.
J Biomol NMR. 2003 Aug;26(4):335-44. doi: 10.1023/a:1024078926886.
We have developed a tool for computer-assisted assignments of protein NMR spectra from triple resonance data. The program is designed to resemble established manual assignment procedures as closely as possible. IBIS exports its results in XEASY format. Thus, using IBIS the operator has continuous visual and accounting control over the progress of the assignment procedure. IBIS achieves complete assignments for those residues that exhibit sequential triple resonance connectivities within a few hours or days.
我们开发了一种工具，用于根据三重共振数据对蛋白质核磁共振谱进行计算机辅助归属。该程序的设计尽可能类似于既定的手动归属程序。IBIS以XEASY格式输出其结果。因此，使用IBIS，操作人员可以对归属过程的进展进行持续的可视化和核算控制。对于那些在数小时或数天内表现出连续三重共振连接性的残基，IBIS能够实现完全归属。
