Ogaĭ V B, Novoselova E G, Fesenko E E
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290 Russia.
Biofizika. 2003 May-Jun;48(3):511-20.
It was found that single total-body exposure to electromagnetic centimeter waves (8.15-18 GHz, 1 microW/cm2, 5 h) stimulated the proliferation of mouse T and B splenic lymphocytes. The same effects were observed upon in vivo treatment of rats for 5 h with millimeter waves (42.2 GHz, amplitude modulation 10 Hz, 1 microW/cm2). The whole-body irradiation with centimeter or millimeter waves did not cause any significant changes in natural activity of killer cells. The cellular responses induced by the irradiation of isolated animal cells in vitro did not coincide with those revealed after the total-body irradiation of animals. Thus, the in vitro irradiation of natural killer cells to millimeter waves for 1 h increased their cytotoxic activity whereas, after treatment to centimeter waves for the same time, the activity of killer cells did not change. On the contrary, irradiation of T and B lymphocytes with millimeter waves (42.2 GHz, amplitude modulation 10 Hz, 1 microW/cm2, 1 h) suppressed the blasttransformation of cells. The results show a higher immunostimulative potential of centimeter waves as compared to millimeter waves.
研究发现，单次全身暴露于电磁厘米波（8.15 - 18 GHz，1微瓦/平方厘米，5小时）可刺激小鼠脾脏T淋巴细胞和B淋巴细胞的增殖。用毫米波（42.2 GHz，调幅10 Hz，1微瓦/平方厘米）对大鼠进行5小时的体内治疗也观察到了相同的效果。用厘米波或毫米波进行全身照射不会使杀伤细胞的自然活性发生任何显著变化。体外对分离的动物细胞进行照射所诱导的细胞反应与对动物进行全身照射后所显示的反应不一致。因此，体外将自然杀伤细胞照射毫米波1小时会增加其细胞毒性活性，而在相同时间内照射厘米波后，杀伤细胞的活性没有变化。相反，用毫米波（42.2 GHz，调幅10 Hz，1微瓦/平方厘米，1小时）照射T淋巴细胞和B淋巴细胞会抑制细胞的母细胞转化。结果表明，与毫米波相比，厘米波具有更高的免疫刺激潜力。
