成人低级别胶质瘤患者放疗的神经认知效应
The neurocognitive effects of radiation in adult low-grade glioma patients.
作者信息
Brown Paul D, Buckner Jan C, Uhm Joon H, Shaw Edward G
机构信息
Division of Radiation Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
出版信息
Neuro Oncol. 2003 Jul;5(3):161-7. doi: 10.1215/S1152851702000431.
Abstract
Radiotherapy is a component of the treatment regimen for the majority of patients with low-grade gliomas. Therefore, the effect of radiotherapy on the long-term cognitive performance of these patients is a major concern. This article reviews the neurocognitive effects of radiotherapy on patients with low-grade gliomas. The weight of evidence suggests only sporadic, limited neurocognitive damage from focal radiotherapy at the doses usually prescribed for low-grade gliomas.
摘要
放射治疗是大多数低级别胶质瘤患者治疗方案的一个组成部分。因此，放射治疗对这些患者长期认知功能的影响是一个主要关注点。本文综述了放射治疗对低级别胶质瘤患者的神经认知影响。现有证据表明，在通常为低级别胶质瘤规定的剂量下，局部放射治疗只会造成偶发性、有限的神经认知损害。
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