Goldberger J, Brooks R, Kadish A
Department of Medicine, Northwestern University Medical School, Chicago, Illinois.
Pacing Clin Electrophysiol. 1992 Dec;15(12):2270-82. doi: 10.1111/j.1540-8159.1992.tb04171.x.
The physiology of atypical atrioventricular junctional reentrant tachycardia (AVJRT) occurring following catheter modification of the AV node is poorly defined. Six patients undergoing radiofrequency current catheter modification of the AV node had inducible atypical AVJRT before or after AV nodal modification. Typical AVJRT was differentiated from atypical AVJRT by a ventriculoatrial (VA) time < 60 msec in the His-bundle electrogram recording. Five of six patients had typical AVJRT and two had atypical AVJRT prior to AV nodal modification. Following anterior approach AV nodal modification, previously undetected atypical AVJRT was induced in four patients. Earliest retrograde atrial activation in the posterior septum was documented in all patients with atypical AVJRT prior to modification and in three of four patients with atypical AVJRT following modification. The AH intervals during tachycardia were 320 +/- 52 msec in typical AVJRT, 88 +/- 33 msec in the premodification atypical AVJRTs, and 172 +/- 12 msec in the postmodification atypical AVJRTs (P = 0.0001). The AH/HA ratios were 4.1 +/- 0.9 in typical AVJRT, 0.5 +/- 0.2 in the premodification atypical AVJRTs, and 0.9 +/- 0.2 in the postmodification atypical AVJRTs (P = 0.0001). Two patients with postmodification atypical AVJRT underwent further posterior approach AV node modification that resulted in VA block. One patient with postmodification atypical AVJRT had further anterior approach AV nodal modification that resulted in heart block. The retrograde limb of the atypical AVJRT seen following anterior approach AV nodal modification is a posterior, slow pathway.
房室结导管改良后发生的非典型房室交界区折返性心动过速(AVJRT)的生理机制尚不清楚。6例接受房室结射频电流导管改良的患者在房室结改良前后可诱发非典型AVJRT。在希氏束电图记录中,心室心房(VA)时间<60毫秒可将典型AVJRT与非典型AVJRT区分开来。6例患者中有5例在房室结改良前有典型AVJRT,2例有非典型AVJRT。在前路房室结改良后,4例患者诱发了先前未检测到的非典型AVJRT。在改良前所有非典型AVJRT患者以及改良后4例非典型AVJRT患者中的3例中,均记录到后间隔最早的逆向心房激动。典型AVJRT心动过速期间的AH间期为320±52毫秒,改良前非典型AVJRT为88±33毫秒,改良后非典型AVJRT为172±12毫秒(P = 0.0001)。典型AVJRT的AH/HA比值为4.1±0.9,改良前非典型AVJRT为0.5±0.2,改良后非典型AVJRT为0.9±0.2(P = 0.0001)。2例改良后非典型AVJRT患者接受了进一步的后路房室结改良,导致VA阻滞。1例改良后非典型AVJRT患者接受了进一步的前路房室结改良,导致心脏阻滞。前路房室结改良后出现的非典型AVJRT的逆向支是一条后向的慢径路。