Matsuyama Katsuhiko, Matsumoto Masahiko, Sugita Takaaki, Nishizawa Junichiro, Tokuda Yoshiyuki, Matsuo Takehiko
Department of Cardiovascular Surgery, Tenri Hospital, Tenri, Nara, Japan.
Ann Thorac Surg. 2003 Jun;75(6):1826-8. doi: 10.1016/s0003-4975(03)00028-6.
Whether preoperative tricuspid regurgitation (TR) will regress or progress late after surgery is unknown. The aim of this study was to evaluate predictors of significant TR late after mitral valve surgery.
A retrospective analysis was performed on a total of 174 patients who underwent mitral valve surgery without tricuspid valve surgery. Preoperatively, 46 patients (26%) had 2+ TR, and 128 patients (74%) had 1+ or less TR. Postoperative 3+ TR was considered significant TR. Variables were used to evaluate predictors of TR development by univariate or multivariate analysis.
The mean follow-up was 8.2 years (range 1.0 to 14.5 years) after surgery. There was progressive TR (3+ or more) in 28 patients (16%) during the follow-up period. In univariate analysis, atrial fibrillation, rheumatic etiology, huge left atrium, left ventricular dysfunction, and preoperative 2+ TR were significant risk factors for TR development. Multivariate analysis identified preoperative 2+ TR, atrial fibrillation, and huge left atrium as statistically significant predictors for late TR after surgery.
Aggressive repair of accompanying TR should be undertaken at the time of initial surgery in patients with huge left atrium or atrial fibrillation, even if preoperative TR is 2+.
术前三尖瓣反流(TR)在术后晚期是会消退还是进展尚不清楚。本研究的目的是评估二尖瓣手术后晚期严重TR的预测因素。
对总共174例未进行三尖瓣手术的二尖瓣手术患者进行回顾性分析。术前,46例患者(26%)有2+级TR,128例患者(74%)有1+级或更低级别的TR。术后3+级TR被认为是严重TR。通过单因素或多因素分析使用变量来评估TR发展的预测因素。
术后平均随访8.2年(范围1.0至14.5年)。随访期间有28例患者(16%)出现进行性TR(3+级或更高)。在单因素分析中,心房颤动、风湿病因、巨大左心房、左心室功能障碍和术前2+级TR是TR发展的显著危险因素。多因素分析确定术前2+级TR、心房颤动和巨大左心房是术后晚期TR的统计学显著预测因素。
对于有巨大左心房或心房颤动的患者,即使术前TR为2+级,在初次手术时也应积极修复伴发的TR。