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三尖瓣反流的外科治疗:一种减少三尖瓣反流复发的新算法。

Surgical management of tricuspid regurgitation: a new algorithm to minimise recurrent tricuspid regurgitation.

机构信息

Universidad de Granada, Granada, Spain

Cardiology, Hospital Universitario Virgen de las Nieves, Granada, Spain.

出版信息

Open Heart. 2022 Jul;9(2). doi: 10.1136/openhrt-2022-002011.

DOI:10.1136/openhrt-2022-002011
PMID:35878960
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9328083/
Abstract

INTRODUCTION

Recurrent tricuspid regurgitation (TR) is frequently observed after cardiac surgery; however, the correct approach remains controversial. We developed an algorithm for action on the tricuspid valve (TV) and conducted a 1-year follow-up study. The aim was to assess the efficacy of the algorithm to minimise residual TR after TV surgery. The hypothesis was that the TR rate at 1 year would be reduced by selecting the surgical approach in accordance with a set of preoperative clinical and echocardiographic variables.

METHODS

A prospective, observational, single-centre study was performed in 76 consecutive patients with TV involvement. A protocol was designed for their inclusion, and data on their clinical and echocardiographic characteristics were gathered at 3 months and 1-year postsurgery. The treatment of patients depended on the degree of TR. Surgery was performed in all patients with severe or moderate-to-severe TR and in those with mild or moderate TR alongside the presence of certain clinical or echocardiographic factors. They underwent annuloplasty or extended valve repair when the TV was distorted. If repair techniques were not feasible, a prosthesis was implanted. Residual TR rates were compared with published reports, and predictors of early/late mortality and residual TR were evaluated.

RESULTS

TR was functional in 69.9% of patients. Rigid ring annuloplasty was performed in 35.7% of patients, De Vega annuloplasty in 27.1%, extended repair in 11.4% and prosthetic replacement in 25.7%. TR was moderate or worse in 8.19% of patients (severe in 3.27%) at 1 year postintervention. No clinical, surgical or epidemiological variables were significantly associated with residual TR persistence, although annulus diameter showed a close-to-significant association. Total mortality was 12.85% for all causes and 10% for cardiovascular causes. In multivariate analysis, left ventricular ejection fraction was related to both early and late mortality.

CONCLUSIONS

Severe residual TR was significantly less frequent than reported in other series, being observed in less than 4% of patients at 1-year postsurgery.

摘要

简介

心脏手术后常发生三尖瓣反流(TR)复发;然而,正确的处理方法仍存在争议。我们制定了三尖瓣(TV)手术的处理方案,并进行了为期 1 年的随访研究。目的是评估该方案在最小化 TV 手术后残余 TR 方面的疗效。假设根据术前临床和超声心动图变量选择手术方法可降低 1 年后 TR 发生率。

方法

对 76 例 TV 受累的连续患者进行前瞻性、观察性、单中心研究。设计了一个方案来纳入这些患者,并在术后 3 个月和 1 年收集他们的临床和超声心动图特征数据。患者的治疗取决于 TR 的程度。所有重度或中重度 TR 患者以及轻度或中重度 TR 合并某些临床或超声心动图因素的患者均行手术治疗。TV 变形时行瓣环成形术或扩展瓣叶修复术。如果修复技术不可行,则植入假体。与已发表的报告比较残余 TR 发生率,并评估早期/晚期死亡率和残余 TR 的预测因素。

结果

69.9%的患者为功能性 TR。35.7%的患者行刚性环瓣环成形术,27.1%行 De Vega 瓣环成形术,11.4%行扩展修复术,25.7%行假体置换术。术后 1 年,8.19%(3.27%为重度)的患者 TR 为中重度或更差。尽管瓣环直径接近显著相关,但没有临床、手术或流行病学变量与残余 TR 持续存在显著相关。所有原因的总死亡率为 12.85%,心血管原因的死亡率为 10%。多变量分析显示,左心室射血分数与早期和晚期死亡率均相关。

结论

严重残余 TR 明显少于其他系列报道,术后 1 年时不足 4%的患者存在严重残余 TR。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e031/9328083/de9ce497fa2a/openhrt-2022-002011f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e031/9328083/14c2e1280a18/openhrt-2022-002011f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e031/9328083/de9ce497fa2a/openhrt-2022-002011f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e031/9328083/14c2e1280a18/openhrt-2022-002011f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e031/9328083/de9ce497fa2a/openhrt-2022-002011f02.jpg

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本文引用的文献

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2021 ESC/EACTS Guidelines for the management of valvular heart disease.2021年欧洲心脏病学会/欧洲心胸外科学会心脏瓣膜病管理指南。
Eur J Cardiothorac Surg. 2021 Oct 22;60(4):727-800. doi: 10.1093/ejcts/ezab389.
2
Progression of Tricuspid Regurgitation After Surgery for Ischemic Mitral Regurgitation.缺血性二尖瓣反流手术后三尖瓣反流的进展。
J Am Coll Cardiol. 2021 Feb 16;77(6):713-724. doi: 10.1016/j.jacc.2020.11.066.
3
2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
2020美国心脏病学会/美国心脏协会瓣膜性心脏病患者管理指南:美国心脏病学会/美国心脏协会临床实践指南联合委员会报告
Circulation. 2021 Feb 2;143(5):e72-e227. doi: 10.1161/CIR.0000000000000923. Epub 2020 Dec 17.
4
Outcomes of Guideline-Directed Concomitant Annuloplasty for Functional Tricuspid Regurgitation.指南指导下功能性三尖瓣反流同期成形术的结果。
Ann Thorac Surg. 2020 Apr;109(4):1227-1232. doi: 10.1016/j.athoracsur.2019.07.035. Epub 2019 Aug 31.
5
Outcomes of patients with severe tricuspid regurgitation and congestive heart failure.严重三尖瓣反流和充血性心力衰竭患者的结局。
Heart. 2019 Dec;105(23):1813-1817. doi: 10.1136/heartjnl-2019-315004. Epub 2019 Aug 17.
6
Outcomes after surgery for functional tricuspid regurgitation: a systematic review and meta-analysis.功能性三尖瓣反流患者行手术治疗后的结局:系统评价和荟萃分析。
Eur Heart J Qual Care Clin Outcomes. 2020 Jan 1;6(1):10-18. doi: 10.1093/ehjqcco/qcz032.
7
Predictors and Outcomes of Persistent Tricuspid Regurgitation After Transcatheter Aortic Valve Implantation.经导管主动脉瓣置换术后持续性三尖瓣反流的预测因素和结局。
Am J Cardiol. 2019 Sep 1;124(5):772-780. doi: 10.1016/j.amjcard.2019.05.066. Epub 2019 Jun 10.
8
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Mayo Clin Proc. 2019 Oct;94(10):2032-2039. doi: 10.1016/j.mayocp.2019.04.036. Epub 2019 Jul 3.
9
Surgery Does Not Improve Survival in Patients With Isolated Severe Tricuspid Regurgitation.孤立性重度三尖瓣反流患者手术治疗并不能改善生存。
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