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[Liatek丙肝病毒检测:用于确认抗丙肝病毒抗体存在的六抗原检测]

[Liatek HCV: the six-antigen test for confirmation of the presence of anti-HCV antibodies].

作者信息

Juszczyk J, Flieger J, Migdalski P, Skalisz H

机构信息

Klinika Chorób Zakaznych Akademii Medycznej im., Poznaniu.

出版信息

Przegl Epidemiol. 1992;46(1-2):11-7.

PMID:1282266
Abstract

Fifty eight anti-HCV repeatable positive (the UBI HCV EIA, Microelisa test Organon Teknika) blood donors were tested using LIATEK-HCV EIA (Organon Teknika). The test was constructed using synthetic polypeptides renders possible to conduct separate investigation antibodies against structural and nonstructural antigens of HCV. In 51/58 (88 per cent) cases was agreement of the results with the UBI test, in 3/58 (5.1 per cent) results were negative, and in 4/58 (6.9 per cent) undetermined. In 90 per cent of the seropositive reactivity developed with four to six antigens. The most frequent "serological pattern" was anti: NS4, C1, C2, C3, C4 (31 per cent) and anti: NS4, NS5, C1, C2, C3, C4 (23.5 per cent).

摘要

对58名抗丙型肝炎病毒反复呈阳性(使用欧加农公司的UBI HCV EIA微酶免疫检测法)的献血者,采用LIATEK - HCV EIA(欧加农公司)进行检测。该检测采用合成多肽构建,使得能够分别研究针对丙型肝炎病毒结构和非结构抗原的抗体。在51/58(88%)的病例中,结果与UBI检测一致,3/58(5.1%)的结果为阴性,4/58(6.9%)的结果不确定。在90%的血清阳性反应中,有四至六种抗原产生反应。最常见的“血清学模式”是抗:NS4、C1、C2、C3、C4(31%)和抗:NS4、NS5、C1、C2、C3、C4(23.5%)。

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