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第二代检测血清学阳性人群中针对丙型肝炎结构和非结构抗原的抗丙型肝炎病毒抗体

[Anti-HCV antibodies against the structural and nonstructural antigens of hepatitis C in people seropositive in the second generation test].

作者信息

Juszczyk J, Flieger J, Migdalski P, Skalisz H

机构信息

Klinika Chorób Zakaźnych AM, Poznaniu im. K. Marcinkowskiego.

出版信息

Przegl Epidemiol. 1992;46(3):159-65.

PMID:1284256
Abstract

Forty six anti-HCV repeatable positive (the 2nd generation Abbott EIA test) adults, among which 26 were blood donors and 19 were patients with chronic hepatitis, were tested using Abbott HCV EIA Supplemental Assay. The test renders possible to conduct separate investigation antibodies against structural and nonstructural antigens of HCV. In 44/45 (97.8 per cent) cases was an agreement of the results with the 2nd generation test. In the most of cases (80 per cent) both types of antibodies were present. However, in 20 per cent of blood donors the antibodies against structural HCV antigen were not present whereas all the chronic hepatitis patients had these type of antibodies.

摘要

46名抗丙型肝炎病毒反复呈阳性(采用第二代雅培酶免疫分析法检测)的成年人接受了雅培丙型肝炎病毒酶免疫补充检测,其中26名是献血者,19名是慢性肝炎患者。该检测使得能够分别检测针对丙型肝炎病毒结构和非结构抗原的抗体。在44/45(97.8%)的病例中,检测结果与第二代检测结果一致。在大多数病例(80%)中,两种抗体均存在。然而,20%的献血者不存在针对丙型肝炎病毒结构抗原的抗体,而所有慢性肝炎患者均有这类抗体。

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