用于核酸折叠和杂交预测的Mfold网络服务器。
Mfold web server for nucleic acid folding and hybridization prediction.
作者信息
Zuker Michael
机构信息
Department of Mathematical Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
出版信息
Nucleic Acids Res. 2003 Jul 1;31(13):3406-15. doi: 10.1093/nar/gkg595.
Abstract
The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids. The objective of this web server is to provide easy access to RNA and DNA folding and hybridization software to the scientific community at large. By making use of universally available web GUIs (Graphical User Interfaces), the server circumvents the problem of portability of this software. Detailed output, in the form of structure plots with or without reliability information, single strand frequency plots and 'energy dot plots', are available for the folding of single sequences. A variety of 'bulk' servers give less information, but in a shorter time and for up to hundreds of sequences at once. The portal for the mfold web server is http://www.bioinfo.rpi.edu/applications/mfold. This URL will be referred to as 'MFOLDROOT'.
摘要
简称为“mfold网络服务器”的软件包含多个密切相关的应用程序，可通过万维网（WWW）预测单链核酸的二级结构。该网络服务器的目标是为广大科学界提供便捷的RNA和DNA折叠及杂交软件。通过使用普遍可用的网络图形用户界面（GUI），该服务器解决了此软件的可移植性问题。对于单序列折叠，可提供详细的输出结果，形式包括带有或不带有可靠性信息的结构示意图、单链频率图和“能量点图”。各种“批量”服务器提供的信息较少，但速度更快，可一次性处理多达数百个序列。mfold网络服务器的入口网址为http://www.bioinfo.rpi.edu/applications/mfold 。此网址将被称为“MFOLDROOT”。
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