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在ALGGEN服务器上识别生物序列中的模式:PROMO和MALGEN。

Identification of patterns in biological sequences at the ALGGEN server: PROMO and MALGEN.

作者信息

Farré Domènec, Roset Romà, Huerta Mario, Adsuara José E, Roselló Llorenç, Albà M Mar, Messeguer Xavier

机构信息

Computing Unit, Institut de Recerca Oncològica, L'Hospitalet, Spain.

出版信息

Nucleic Acids Res. 2003 Jul 1;31(13):3651-3. doi: 10.1093/nar/gkg605.

Abstract

In this paper we present several web-based tools to identify conserved patterns in sequences. In particular we present details on the functionality of PROMO version 2.0, a program for the prediction of transcription factor binding site in a single sequence or in a group of related sequences and, of MALGEN, a tool to visualize sequence correspondences among long DNA sequences. The web tools and associated documentation can be accessed at http://www.lsi.upc.es/~alggen (RESEARCH link).

摘要

在本文中,我们展示了几种基于网络的工具,用于识别序列中的保守模式。特别地,我们详细介绍了PROMO 2.0版本的功能,这是一个用于预测单个序列或一组相关序列中转录因子结合位点的程序,以及MALGEN,一种用于可视化长DNA序列间序列对应关系的工具。这些网络工具及相关文档可通过http://www.lsi.upc.es/~alggen(研究链接)访问。

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