• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold.霍乱弧菌蛋白VC0424的溶液结构：类铁氧化还原蛋白折叠的一种变体
Protein Sci. 2003 Jul;12(7):1556-61. doi: 10.1110/ps.03108103.
2
The crystal structure of zinc-containing ferredoxin from the thermoacidophilic archaeon Sulfolobus sp. strain 7.嗜热嗜酸古菌硫磺矿硫化叶菌菌株7中含锌铁氧化还原蛋白的晶体结构。
Biochemistry. 1997 Feb 11;36(6):1505-13. doi: 10.1021/bi961966j.
3
Structure of Synechococcus elongatus [Fe2S2] ferredoxin in solution.溶液中聚球藻[Fe2S2]铁氧化还原蛋白的结构。
Biochemistry. 1996 Oct 1;35(39):12831-41. doi: 10.1021/bi961144m.
4
The crystal structure of the periplasmic domain of the type II secretion system protein EpsM from Vibrio cholerae: the simplest version of the ferredoxin fold.霍乱弧菌II型分泌系统蛋白EpsM周质结构域的晶体结构：铁氧化还原蛋白折叠的最简单形式。
J Mol Biol. 2004 Apr 30;338(3):585-96. doi: 10.1016/j.jmb.2004.01.064.
5
Molecular model of the solution structure for the paramagnetic four-iron ferredoxin from the hyperthermophilic archaeon Thermococcus litoralis.嗜热古菌嗜热栖热放线菌中顺磁性四铁铁氧化还原蛋白溶液结构的分子模型。
Biochemistry. 1996 Sep 3;35(35):11319-28. doi: 10.1021/bi960783u.
6
An NMR-derived model for the solution structure of oxidized Thermotoga maritima 1[Fe4-S4] ferredoxin.氧化型嗜热栖热菌1[Fe4-S4]铁氧化还原蛋白溶液结构的核磁共振衍生模型。
Eur J Biochem. 1996 May 1;237(3):726-35. doi: 10.1111/j.1432-1033.1996.0726p.x.
7
Solution 1H NMR determination of secondary structure for the three-iron form of ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus.通过溶液¹H核磁共振法测定嗜热古菌激烈火球菌铁氧化还原蛋白三铁形式的二级结构。
Biochemistry. 1994 May 24;33(20):6316-26. doi: 10.1021/bi00186a035.
8
1H nuclear-magnetic-resonance investigation of oxidized Fe4S4 ferredoxin from Thermotoga maritima. Hyperfine-shifted resonances, sequence-specific assignments and secondary structure.嗜热栖热菌氧化型Fe4S4铁氧化还原蛋白的1H核磁共振研究。超精细位移共振、序列特异性归属及二级结构
Eur J Biochem. 1995 May 1;229(3):658-68. doi: 10.1111/j.1432-1033.1995.tb20511.x.
9
A two-alpha-helix extra domain mediates the halophilic character of a plant-type ferredoxin from halophilic archaea.一个双α螺旋额外结构域介导了嗜盐古菌中一种植物型铁氧化还原蛋白的嗜盐特性。
Biochemistry. 2005 Jan 11;44(1):29-39. doi: 10.1021/bi0485169.
10
Structural similarities between the N-terminal domain of Clostridium pasteurianum hydrogenase and plant-type ferredoxins.巴氏芽孢杆菌氢化酶N端结构域与植物型铁氧化还原蛋白之间的结构相似性。
Biochemistry. 1999 Feb 9;38(6):1938-43. doi: 10.1021/bi982416j.

引用本文的文献

1
Preliminary crystallographic analysis of RraB from Escherichia coli.来自大肠杆菌的RraB的初步晶体学分析。
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Nov;69(Pt 11):1268-71. doi: 10.1107/S1744309113026559. Epub 2013 Oct 30.
2
SPARTA+: a modest improvement in empirical NMR chemical shift prediction by means of an artificial neural network.SPARTA+：通过人工神经网络对经验核磁共振化学位移预测的适度改进。
J Biomol NMR. 2010 Sep;48(1):13-22. doi: 10.1007/s10858-010-9433-9. Epub 2010 Jul 14.
3
Transcriptional regulation of the Escherichia coli gene rraB, encoding a protein inhibitor of RNase E.大肠杆菌基因rraB的转录调控，该基因编码核糖核酸酶E的一种蛋白质抑制剂。
J Bacteriol. 2009 Nov;191(21):6665-74. doi: 10.1128/JB.00344-09. Epub 2009 Aug 28.
4
The solution structure of the core of mesoderm development (MESD), a chaperone for members of the LDLR-family.中胚层发育核心蛋白（MESD）的溶液结构，MESD是低密度脂蛋白受体（LDLR）家族成员的伴侣蛋白。
J Struct Funct Genomics. 2006 Dec;7(3-4):131-8. doi: 10.1007/s10969-007-9016-5. Epub 2007 Mar 7.

本文引用的文献

1
Solution NMR structure of ribosome-binding factor A (RbfA), a cold-shock adaptation protein from Escherichia coli.核糖体结合因子A（RbfA）的溶液核磁共振结构，RbfA是一种来自大肠杆菌的冷休克适应蛋白。
J Mol Biol. 2003 Mar 21;327(2):521-36. doi: 10.1016/s0022-2836(03)00061-5.
2
The Xplor-NIH NMR molecular structure determination package.Xplor-NIH核磁共振分子结构测定软件包。
J Magn Reson. 2003 Jan;160(1):65-73. doi: 10.1016/s1090-7807(02)00014-9.
3
ConSurf: identification of functional regions in proteins by surface-mapping of phylogenetic information.ConSurf：通过系统发育信息的表面映射识别蛋白质中的功能区域。
Bioinformatics. 2003 Jan;19(1):163-4. doi: 10.1093/bioinformatics/19.1.163.
4
Factors influencing the identification of transcription factor binding sites by cross-species comparison.跨物种比较影响转录因子结合位点识别的因素。
Genome Res. 2002 Oct;12(10):1523-32. doi: 10.1101/gr.323602.
5
A novel ligand-binding domain involved in regulation of amino acid metabolism in prokaryotes.一种参与原核生物氨基酸代谢调控的新型配体结合结构域。
J Biol Chem. 2002 Oct 4;277(40):37464-8. doi: 10.1074/jbc.M206063200. Epub 2002 Jul 23.
6
The ACT domain family.ACT结构域家族。
Curr Opin Struct Biol. 2001 Dec;11(6):694-700. doi: 10.1016/s0959-440x(01)00272-x.
7
ConSurf: an algorithmic tool for the identification of functional regions in proteins by surface mapping of phylogenetic information.ConSurf：一种通过系统发育信息的表面映射来识别蛋白质功能区域的算法工具。
J Mol Biol. 2001 Mar 16;307(1):447-63. doi: 10.1006/jmbi.2000.4474.
8
DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli.对大肠杆菌中影响色氨酸代谢的生理和遗传变化作出反应的基因表达的DNA微阵列分析。
Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12170-5. doi: 10.1073/pnas.220414297.
9
A gene cluster for the synthesis of serotype d-specific polysaccharide antigen in Actinobacillus actinomycetemcomitans.伴放线放线杆菌中血清型d特异性多糖抗原合成的基因簇。
Biochim Biophys Acta. 2000 Sep 7;1493(1-2):259-63. doi: 10.1016/s0167-4781(00)00179-2.
10
An integrated approach to the analysis and modeling of protein sequences and structures. I. Protein structural alignment and a quantitative measure for protein structural distance.一种用于蛋白质序列和结构分析与建模的综合方法。I. 蛋白质结构比对及蛋白质结构距离的定量度量。
J Mol Biol. 2000 Aug 18;301(3):665-78. doi: 10.1006/jmbi.2000.3973.

霍乱弧菌蛋白VC0424的溶液结构：类铁氧化还原蛋白折叠的一种变体

Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold.

作者信息

Ramelot Theresa A, Ni Shuisong, Goldsmith-Fischman Sharon, Cort John R, Honig Barry, Kennedy Michael A

机构信息

Biological Sciences Division, Pacific Northwest National Laboratory, EMSL 2569 K8-98, 3335 Q Avenue, Richland, WA 99352, USA.

出版信息

Protein Sci. 2003 Jul;12(7):1556-61. doi: 10.1110/ps.03108103.

DOI:10.1110/ps.03108103
PMID:12824501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2323929/
Abstract

The structure of Vibrio cholerae protein VC0424 was determined by NMR spectroscopy. VC0424 belongs to a conserved family of bacterial proteins of unknown function (COG 3076). The structure has an alpha-beta sandwich architecture consisting of two layers: a four-stranded antiparallel beta-sheet and three side-by-side alpha-helices. The secondary structure elements have the order alphabetaalphabetabetaalphabeta along the sequence. This fold is the same as the ferredoxin-like fold, except with an additional long N-terminal helix, making it a variation on this common motif. A cluster of conserved surface residues on the beta-sheet side of the protein forms a pocket that may be important for the biological function of this conserved family of proteins.

摘要

霍乱弧菌蛋白VC0424的结构通过核磁共振光谱法测定。VC0424属于一个功能未知的细菌保守蛋白家族（COG 3076）。该结构具有α-β三明治结构，由两层组成：一个四链反平行β折叠片和三个并排的α螺旋。二级结构元件沿序列具有αβαβαβαβ的顺序。这种折叠与铁氧化还原蛋白样折叠相同，只是有一个额外的长N端螺旋，使其成为这种常见基序的一种变体。蛋白质β折叠片一侧的一组保守表面残基形成一个口袋，这可能对这个保守蛋白家族的生物学功能很重要。