Lo Y L, Cui S L
Department of Neurology, National Neuroscience Institute, Singapore 169608.
Neuroreport. 2003 Jul 1;14(9):1229-31. doi: 10.1097/00001756-200307010-00008.
Although acupuncture is increasingly utilized for medical therapy, its mechanism of action remains uncertain. We used transcranial magnetic stimulation to demonstrate lateralized effects of motor cortex excitability with this technique. Right-sided reduction in motor cortex excitability and a tendency to the opposite effect on the left side was seen with acupuncture. Sham needle insertions did not result in significant changes of motor cortex excitability. These findings provide new neurophysiological evidence of cortical excitability modulation complementary to findings derived from functional neuroimaging studies.
尽管针灸越来越多地被用于医学治疗，但其作用机制仍不明确。我们使用经颅磁刺激来证明这种技术对运动皮层兴奋性的侧化效应。针灸可使右侧运动皮层兴奋性降低，而对左侧则有相反的作用趋势。假针刺不会导致运动皮层兴奋性的显著变化。这些发现为皮层兴奋性调节提供了新的神经生理学证据，补充了来自功能性神经影像学研究的结果。
