Prifti Edvin, Bonacchi Massimo, Bartolozzi Fabio, Frati Giacomo, Leacche Marzia, Vanini Vittorio
Divisione di Cardiochirurgia, Policlinico Careggi, Firenze, Italy.
Med Sci Monit. 2003 Jun;9(6):RA126-33.
Accessory mitral valve tissue (AcMVT) is a rare congenital malformation causing left ventricular outflow tract obstruction (LVOTO). The analysis of various published reports reveals 90 patients presenting with AcMVT, ranging in age from newborns to 77 years old. Severe LVOTO is present in most cases, though mild LVOTO was found in 15 patients (16.7%), and 3 other patients (3.3%) presented with no LVOTO. In our practice, we found this anomaly in 5 patients; one presenting with severe LVOTO, two with mild LVOTO, and another who developed moderate LVOTO after a myocardial infarction episode. 68 patients (75.5%) underwent cardiac surgery, with a postoperative mortality of 6 (8.9%). Postoperatively, a residual mild gradient across the left ventricular outflow tract was identified in 9 patients (13.2%). Nine other patients (13.2%) required reoperation due to severe LVOTO. Mild-to-moderate postoperative mitral or aortic valve regurgitation was found in 7 (10.3%) and 5 (7.3%) patients, respectively. Based on reported intraoperative findings, we have classified this anomaly as Type I-FIXED TYPE (A - nodular, B - Membranous), Type II-Mobile type (A - Pedunculated, B - leaflet-like). Type IIB is divided into 1) rudimentary chordae and 2) developed chordae. Based in our own experience and after the analysis of various reports, we conclude that patients with AcMVT causing LVOTO may undergo safe mass excision with acceptable postoperative mortality and morbidity. The removal of the AcMVT should in no way compromise mitral valve function, and its excision should be made subject to careful evaluation of the surrounding structures.
二尖瓣附属组织(AcMVT)是一种罕见的先天性畸形,可导致左心室流出道梗阻(LVOTO)。对各种已发表报告的分析显示,有90例患者患有AcMVT,年龄从新生儿到77岁不等。大多数病例存在严重的LVOTO,不过有15例患者(16.7%)发现有轻度LVOTO,另有3例患者(3.3%)没有LVOTO。在我们的临床实践中,我们发现5例患者存在这种异常情况;1例表现为严重的LVOTO,2例为轻度LVOTO,还有1例在心肌梗死发作后出现中度LVOTO。68例患者(75.5%)接受了心脏手术,术后死亡率为6例(8.9%)。术后,9例患者(13.2%)在左心室流出道发现有残余的轻度压差。另外9例患者(13.2%)因严重的LVOTO需要再次手术。分别有7例(10.3%)和5例(7.3%)患者术后出现轻度至中度二尖瓣或主动脉瓣反流。根据报告的术中发现,我们将这种异常情况分为I型 - 固定型(A - 结节状,B - 膜状),II型 - 活动型(A - 有蒂,B - 瓣叶样)。IIB型又分为1)原始腱索型和2)发育腱索型。基于我们自己的经验以及对各种报告的分析,我们得出结论,患有导致LVOTO的AcMVT的患者可以接受安全的大块切除,术后死亡率和发病率在可接受范围内,但切除AcMVT绝不应损害二尖瓣功能,其切除应在仔细评估周围结构的情况下进行。