Odehnal M, Gergelyová K, Pochop P, Hlozánek M
Ocní klinika dĕtí a dospĕlých UK 2. LF a FN Motol, Praha.
Cesk Slov Oftalmol. 2003 Mar;59(2):80-5.
The objective of the work was to compare the effectiveness of transscleral laser photocoagulation and cryocoagulation of the retina in the treatment of retinopathy of premature infants (ROP). During the period from March 1999 to April 2001 at the Ophthalmological Clinic for children and adults in the Motol Faculty Hospital 80 eyes of 40 children with the borderline stage of ROP were treated. In 40 eyes cryocoagulation was performed, in 40 transcleral photocoagulation of the retina. The mean gestation age of the infants on delivery was 28.7 weeks, the postconception age at the time of operation 36.7 weeks. The follow up period varied from 1 to 24 months. All therapeutic provisions were made with premedication and under local anaesthesia. For a stabilized finding without progression we took an adherent retina without subsequent traction changes. Cryocoagulation was successful in 87.5%, laser photocoagulation in 85%. Both methods proved equally effective. In photocoagulation the authors recorded a lower incidence of local complications. General undesirable effects were not recorded in any of the treated children. Transscleral photocoagulation extends contemporary therapeutic possibilities in patients with ROP.
该研究的目的是比较经巩膜激光光凝术和视网膜冷冻术治疗早产儿视网膜病变（ROP）的有效性。1999年3月至2001年4月期间，在Motol医学院医院的儿童和成人眼科诊所，对40例处于ROP临界期的儿童的80只眼睛进行了治疗。其中40只眼睛接受了冷冻术，40只眼睛接受了经巩膜视网膜光凝术。婴儿出生时的平均孕周为28.7周，手术时的孕龄为36.7周。随访期为1至24个月。所有治疗均在术前用药和局部麻醉下进行。对于无进展的稳定结果，我们采用了附着的视网膜且无后续牵引改变。冷冻术的成功率为87.5%，激光光凝术的成功率为85%。两种方法证明同样有效。在光凝术中，作者记录到局部并发症的发生率较低。在任何接受治疗的儿童中均未记录到一般不良影响。经巩膜光凝术扩展了ROP患者的现代治疗可能性。
