Deshpande D A, Chaturvedi M, Gopal L, Ramachandran S, Shanmugasundaram R
Medical and Vision Research Foundations, Chennai, India.
Indian J Ophthalmol. 1998 Mar;46(1):15-9.
This report deals with our experience in the management of threshold retinopathy of prematurity (ROP). A total of 45 eyes of 23 infants were subjected to treatment of threshold ROP. 26.1% of these infants had a birth weight of > 1,500 gm. The preferred modality of treatment was laser indirect photocoagulation, which was facilitated by scleral depression. Cryopexy was done in cases with nondilating pupils or medial haze and was always under general anaesthesia. Retreatment with either modality was needed in 42.2% eyes; in this the skip areas were covered. Total regression of diseases was achieved in 91.1% eyes with no sequelae. All the 4 eyes that progressed to stage 5 despite treatment had zone 1 disease. Major treatment-induced complications did not occur in this series. This study underscores the importance of routine screening of infants upto 2,000 gm birth weight for ROP and the excellent response that is achieved with laser photocoagulation in inducing regression of threshold ROP. Laser is the preferred method of treatment in view of the absence of treatment-related morbidity to the premature infants.
本报告阐述了我们在阈值ROP（早产儿视网膜病变）治疗方面的经验。23名婴儿的45只眼睛接受了阈值ROP治疗。这些婴儿中26.1%出生体重>1500克。首选的治疗方式是间接激光光凝，通过巩膜压迫辅助进行。对于瞳孔不散大或有中度混浊的病例进行冷冻治疗，且总是在全身麻醉下进行。42.2%的眼睛需要用任何一种方式进行再次治疗；在此过程中对跳跃区域进行了覆盖。91.1%的眼睛疾病完全消退且无后遗症。尽管接受了治疗，但进展到5期的4只眼睛均为1区病变。本系列未发生主要的治疗引起的并发症。本研究强调了对出生体重达2000克的婴儿进行ROP常规筛查的重要性，以及激光光凝在诱导阈值ROP消退方面取得的良好效果。鉴于对早产儿无治疗相关的发病率，激光是首选的治疗方法。
