Furdová A, Macák D, Poruban S
Klinika oftalmológie FN a LFUK, Bratislava.
Cesk Slov Oftalmol. 2003 Mar;59(2):119-26.
Carcinoma of the Meibomian gland of the eyelid is very rare with atypical glandular features, that may appear initially as a chalazion formation and then invades the neighbouring tissues.
Demonstration of the importance of surgical excision and histological examination in presence of an apparently harmless tumoral alteration of the eyelids and verifying every case of atypical lesion of the eyelid region. Case presentation No. 1: We report a case of 76-year old woman patients suffering from chronical blepharoconjunctivitis and chronical chalazion many times simply performed excochleation. Histopathological finding of the excision of the tumour showed the presence of carcinoma Meibomian gland (stage G2), the patient refused exenteration and died in 2 month interval. Case presentation No. 2.: 65-year old men with carcinoma linguae 1.sin. (T3 N2 M0) in 1998 after hemiglossectomia, resectionem baseos oris 1.sin. and radiotherapy, came to our clinic with exoftalm and tumor in his right orbit in Jun 2001. CT found tumour 3 x 2 x 2 cm. In September 2001 orbitotomia bicoronalis 1.sin., extirpatio TU orbitae 1.sin. histologically verified karcinoma of Meibomain gland, patient without any problems after operation and radiotherapy.
眼睑睑板腺癌非常罕见，具有非典型腺性特征，最初可能表现为睑板腺囊肿形成，随后侵犯邻近组织。
证明在眼睑出现看似无害的肿瘤性改变时手术切除和组织学检查的重要性，并核实眼睑区域每一例非典型病变病例。病例报告1：我们报告一例76岁女性患者，患有慢性睑结膜炎和慢性睑板腺囊肿，多次单纯行刮除术。肿瘤切除的组织病理学检查显示存在睑板腺癌（G2期），患者拒绝行眼球摘除术，在2个月内死亡。病例报告2：一名65岁男性，1998年因舌癌1.sin.（T3 N2 M0）行半舌切除术、1.sin.口腔底部切除术及放疗，2001年6月因右眼突出和右眼眶肿瘤前来我院就诊。CT发现肿瘤大小为3×2×2 cm。2001年9月行1.sin.双侧冠状开眶术、1.sin.右眼眶肿瘤摘除术，组织学证实为睑板腺癌，患者术后及放疗后无任何问题。
