Antalík M, Bona M, Bágelová J
Institute of Experimental Physics, Slovak Academy of Sciences, Kosice, Czechoslovakia.
Biochem Int. 1992 Dec;28(4):675-82.
Application of heparin, polyadenylate, polyglutamate and polygalacturonate resulted in changes in the electron absorption spectrum of cytochrome c that resembled those after cytochrome c oxidase application at neutral pH. The formed complexes of cytochrome c with polyanions retain the bond of Met-80 with heme iron. Cytochrome c oxidase and the polyanions increased the apparent pKa of alkaline transition of cytochrome c by an order of magnitude.
