Kim C H, King T E
Department of Biology, Rensselaer Polytechnic Institute, Troy, N.Y. 12180.
Biochem Int. 1991 May;24(2):255-62.
The cytochrome c-cytochrome oxidase complex is formed when c reacts with cytochrome oxidase (Kuboyama et al. (1962) Biochem. Biophys. Res. Commun. 9, 534) and the cytochrome c1-cytochrome c complex is formed when c reacts with cytochrome c1 in the presence of the hinge protein (Kim, C.H. and King, T.E. (1981) Biochem. Biophys. Res. Commun. 101, 607). Both complexes are considered to be possible intermediates in electron transfer reaction between these cytochromes. Triply substituted modified cytochrome c by pyridoxal phosphate at lysine residues (Lys-79, 86 and one to be identified) abolishes both complex formations and electron transfer activity with succinate cytochrome c reductase or cytochrome oxidase.
当细胞色素c与细胞色素氧化酶反应时，会形成细胞色素c - 细胞色素氧化酶复合物（久保山等人（1962年），《生物化学与生物物理研究通讯》9卷，第534页）；当细胞色素c在铰链蛋白存在的情况下与细胞色素c1反应时，会形成细胞色素c1 - 细胞色素c复合物（金，C.H.和金，T.E.（1981年），《生物化学与生物物理研究通讯》101卷，第607页）。这两种复合物都被认为是这些细胞色素之间电子转移反应中可能的中间体。赖氨酸残基（Lys - 79、86以及一个待确定的残基）被磷酸吡哆醛三重取代修饰的细胞色素c，会消除与琥珀酸细胞色素c还原酶或细胞色素氧化酶的复合物形成及电子转移活性。
