[中枢神经系统原发性黑色素瘤]
[Primary melanoma of the central nervous system].
作者信息
Zhang Y, Chen L, Wu J, Qin Z, Zhang F
机构信息
Department of Neurosurgery, Huashan Hospital, Shanghai Medical University, China.
出版信息
Zhonghua Wai Ke Za Zhi. 2000 Apr;38(4):283-4.
OBJECTIVE
To investigate the status of diagnosis and treatment of primary melanoma of the central nervous system.
METHODS
Six patients with primary melanoma of the central nervous system underwent surgery in our department between 1969-1999. Clinical presentation, operative findings, histological diagnosis, and prognosis were reviewed.
RESULTS
No typical symptom occurred in these patients. The lesions can mimic meningiomas and acoustic neuromas in location and radiological appearance. Total removal of tumors was only achieved in one case. Histological examination showed malignant lesions in 3 cases and benign lesions in others. Five cases were followed up and only two were alive.
CONCLUSIONS
Primary melanomas are extremely rare tumors of the central nervous system. Surgical removal of the lesion may result in prolonged remission or cure.
目的
探讨中枢神经系统原发性黑色素瘤的诊断和治疗现状。
方法
1969年至1999年间，我科对6例中枢神经系统原发性黑色素瘤患者进行了手术。回顾了临床表现、手术所见、组织学诊断及预后情况。
结果
这些患者均无典型症状。病变在位置和影像学表现上可类似脑膜瘤和听神经瘤。仅1例实现了肿瘤全切。组织学检查显示3例为恶性病变，其他为良性病变。5例进行了随访，仅2例存活。
结论
原发性黑色素瘤是中枢神经系统极为罕见的肿瘤。手术切除病变可能会导致缓解期延长或治愈。
Zotero 插件