Escrig Sos V J, Angel Yepes V, Senent Vizcaíno V
Servicio de Cirugía General. Hospital General de Castellón. Spain.
Rev Esp Enferm Dig. 2003 May;95(5):328-32, 322-7.
a study is made of the course of adhesive small bowel obstruction in an attempt to draw conclusions regarding useful measures for reducing its incidence and severity.
a retrospective study is made of 146 cases of adhesive small bowel obstruction from the last adhesion-related hospital admission of each patient, with an evaluation of Kaplan-Meier survival curve fit to the principal parametric distributions of the disorder.
surgery of the appendix was the type of prior surgery most frequently associated with adhesion occlusion. The mean latency was close to 8 years, with a constant incidence rate of 0.128 cases/patient and year. The initial latency was shorter for colorectal surgery and for prior inframesocolic surgery in general, as well as for conditions of relapse. A prospective follow-up comprising most of the cases (i.e., 95%) could require over 20 years, or up to 10 years to assess the corresponding relapses.
from the clinical research perspective, the best approach to the problem of adhesive small bowel obstruction comprises the evaluation of prophylactic measures against adhesion formation. The more reliable methodological design of investigational studies must be sustained by prospective follow-up supported by hospital admission databases.
对粘连性小肠梗阻的病程进行研究，以得出有关降低其发生率和严重程度的有效措施的结论。
对146例粘连性小肠梗阻患者进行回顾性研究，这些患者均为各自最后一次因粘连相关疾病入院治疗的病例，并评估符合该疾病主要参数分布的Kaplan-Meier生存曲线。
阑尾手术是最常与粘连性肠梗阻相关的既往手术类型。平均潜伏期接近8年，发病率恒定为0.128例/患者·年。结直肠手术以及一般的结肠内手术和复发情况的初始潜伏期较短。对大多数病例（即95%）进行前瞻性随访可能需要20多年，或者评估相应复发情况需要长达10年。
从临床研究角度来看，解决粘连性小肠梗阻问题的最佳方法包括评估预防粘连形成的措施。研究性研究更可靠的方法设计必须通过医院入院数据库支持的前瞻性随访来维持。
