Bragg Jennifer W, Ratner Désirée
Department of Dermatology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA.
Dermatol Surg. 2003 Jul;29(7):766-8. doi: 10.1046/j.1524-4725.2003.29193.x.
Human papillomavirus (HPV) type 2 is generally considered to be a benign viral infection associated with common warts. Other HPV types have been associated with the development of squamous cell carcinomas (SCCs).
To describe a case of HPV type 2 identified in a SCC of the finger in an immunocompetent patient. To our knowledge, this is the first such case reported in the literature.
This is a case report and review of the literature.
Mohs micrographic surgery performed in two stages effectively removed the tumor.
HPV type 2 may play a role in the development of cutaneous SCC. Further epidemiologic and molecular studies of HPV and SCCs will be helpful in determining the role of HPV type 2 in cutaneous oncogenesis.
人乳头瘤病毒2型(HPV-2)通常被认为是一种与寻常疣相关的良性病毒感染。其他HPV类型则与鳞状细胞癌(SCC)的发生有关。
描述一例在免疫功能正常的患者手指SCC中发现HPV-2的病例。据我们所知,这是文献中首次报道的此类病例。
这是一篇病例报告及文献综述。
分两阶段进行的莫氏显微外科手术有效地切除了肿瘤。
HPV-2可能在皮肤SCC的发生中起作用。对HPV和SCC进行进一步的流行病学和分子研究将有助于确定HPV-2在皮肤肿瘤发生中的作用。