Myers Bronwyn, Siegfried Nandi, Parry Charles D H
Alcohol and Drug Abuse Research Group, Medical Research Council, Cape Town.
S Afr Med J. 2003 May;93(5):367-70.
To provide community-level public health surveillance information on over-the-counter (OTC) and prescription medicine misuse.
A retrospective study of OTC and prescription medicine misuse among 9,063 patients from 23 specialist substance abuse treatment centres in Cape Town, South Africa, between 1998 and 2000.
OTC and prescription medicine misuse places a burden on health and social services in South Africa. This is evidenced through the constant demand for treatment for OTC/prescription medicine misuse. Benzodiazepines are the class of medicines for which users most often receive treatment, followed by analgesics. Analgesic misuse is most often accounted for by the use of codeine-containing medicines, many of which are available over the counter. Patients using OTC/prescription medicines as their primary drug of abuse are significantly more likely to be female, and aged over 40 years. In contrast, patients using OTC/prescription medicine as an additional drug of abuse tend to be male and over 40 years of age.
This study points to the need to develop primary health care protocols for detection, management and referral of patients misusing OTC/prescription drugs and the need to debate the re-scheduling of codeine as a prescription-only substance. The study also points to the need for further community-based research on the nature and extent of OTC/prescription drug misuse among the general population.
提供有关非处方药(OTC)和处方药滥用的社区层面公共卫生监测信息。
对1998年至2000年间南非开普敦23家专业药物滥用治疗中心的9063名患者中OTC和处方药滥用情况进行回顾性研究。
OTC和处方药滥用给南非的卫生和社会服务带来负担。对OTC/处方药滥用治疗的持续需求证明了这一点。苯二氮䓬类药物是使用者最常接受治疗的药物类别,其次是镇痛药。镇痛药滥用最常见的原因是使用含可待因的药物,其中许多是非处方药。将OTC/处方药作为主要滥用药物的患者更有可能是女性,且年龄在40岁以上。相比之下,将OTC/处方药作为额外滥用药物的患者往往是男性且年龄超过40岁。
本研究指出有必要制定初级卫生保健方案,用于检测、管理和转诊滥用OTC/处方药的患者,以及有必要讨论将可待因重新列为仅凭处方使用物质的问题。该研究还指出有必要在社区层面进一步研究普通人群中OTC/处方药滥用的性质和程度。