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[受体年龄对使用心脏停搏供体器官进行移植手术的影响]

[Effect of recipient age on transplants performed using organs from donors in asystole].

作者信息

Gómez Vegas Angel, Blázquez Izquierdo Jesús, Bocardo Fajardo Gloria, Fuentes Márquez Isabel, Corral Rosillo Javier, Fernández Pérez Cristina, Silmi Moyano Angel, Resel Estévez Luis

机构信息

Cátedra y Servicio de Urología, Hospital Clínico San Carlos, C/Martín Lagos s/n 28040 Madrid, España.

出版信息

Arch Esp Urol. 2003 May;56(4):379-84.

PMID:12830610
Abstract

OBJECTIVES

To evaluate the influence of receptor's age on the outcomes of kidney transplants with organs from non heart beating donors.

METHODS

Observational study of the historic cohort of 570 kidney transplants performed at the Hospital Clínico San Carlos between 1991 and 1999. Receptor's were divided into two age groups, group 1 younger than 50 years, and group 2 older than 50 years. All organs where harvested from non heart beating donors.

RESULTS

We studied 110 kidney transplants coming from non heart beating donors; 52 belonged to group 1, and 57 to group 2. Three-year patient survival for receptor's younger than 50 years was 100%. The probability of three-year survival for receptor's older than 50 years was 79.39% (p 0.07). Graft survival was 88.46%, 86.54%, and 86.54% at 12, 24, and 36 months respectively for receptor's younger than 50 years. When receptors were older than 50 years the probability of functioning graft in the same periods of time was 89.20%, 89.20%, and 86.32% respectively.

CONCLUSIONS

Receptor's age doesn't seem to influence graft survival when kidneys from non heart beating donors are used.

摘要

目的

评估受体年龄对非心脏跳动供体肾脏移植结局的影响。

方法

对1991年至1999年在圣卡洛斯临床医院进行的570例肾脏移植的历史队列进行观察性研究。将受体分为两个年龄组,第1组年龄小于50岁,第2组年龄大于50岁。所有器官均取自非心脏跳动供体。

结果

我们研究了110例来自非心脏跳动供体的肾脏移植;52例属于第1组,57例属于第2组。年龄小于50岁的受体三年患者生存率为100%。年龄大于50岁的受体三年生存率为79.39%(p = 0.07)。年龄小于50岁的受体在12、24和36个月时的移植肾生存率分别为88.46%、86.54%和86.54%。当受体年龄大于50岁时,在相同时间段内移植肾功能的概率分别为89.20%、89.20%和86.32%。

结论

使用非心脏跳动供体的肾脏时,受体年龄似乎不影响移植肾生存率。

相似文献

1
[Effect of recipient age on transplants performed using organs from donors in asystole].[受体年龄对使用心脏停搏供体器官进行移植手术的影响]
Arch Esp Urol. 2003 May;56(4):379-84.
2
[Influence of recipient age on renal transplantation performed with organs coming from child donors].[受者年龄对接受来自儿童供体器官的肾移植手术的影响]
Arch Esp Urol. 2003 Jun;56(5):491-5.
3
Outcomes of kidney transplants from non-heart-beating deceased donors as reported to the Japan Organ Transplant Network from April 1995-December 2003: a multi-center report.1995年4月至2003年12月期间向日本器官移植网络报告的非心脏死亡供体肾移植结果:多中心报告。
Clin Transpl. 2004:91-102.
4
[Renal transplantation in donors over 60 years of age].
Arch Esp Urol. 2003 Mar;56(2):151-9.
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Non-heart beating donors.非心脏跳动供体
Nephrol Dial Transplant. 2004 Jun;19 Suppl 3:iii26-31. doi: 10.1093/ndt/gfh1011.
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Transplantation. 2008 Jun 15;85(11):1573-9. doi: 10.1097/TP.0b013e31817059a1.
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Transplantation. 2007 May 15;83(9):1193-9. doi: 10.1097/01.tp.0000261710.53848.51.
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Kidney transplantation from non-heart-beating donors: analysis of organ procurement and outcome.来自非心脏跳动供体的肾移植:器官获取与结果分析
Transplant Proc. 2004 Sep;36(7):1888-90. doi: 10.1016/j.transproceed.2004.06.030.
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Role of donor age and acute rejection episodes on long-term graft survival in cadaveric kidney transplantations.供体年龄和急性排斥反应发作对尸体肾移植长期移植肾存活的作用。
Transplant Proc. 2005 Sep;37(7):2954-6. doi: 10.1016/j.transproceed.2005.08.038.