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[受者年龄对接受来自儿童供体器官的肾移植手术的影响]

[Influence of recipient age on renal transplantation performed with organs coming from child donors].

作者信息

Gómez Vegas Angel, Blázquez Izquierdo Jesús, Bocardo Fajardo Gloria, Jiménez Penick Francisco José, Delgado Martín José Angel, Fernández Pérez Cristina, Silmi Moyano Angel, Resel Estevez Luis

机构信息

Cátedra y Servicio de Urología, Hospital Clínico San Carlos, C/Martín Lagos s/n 28040 Madrid, España.

出版信息

Arch Esp Urol. 2003 Jun;56(5):491-5.

PMID:12918306
Abstract

OBJECTIVES

To evaluate the influence of receptor's age on the outcomes of kidney transplants with organs from donors below the age of three years and/or weighting less than 15 Kg.

METHODS

We retrospectively studied the renal transplants with organs from donors below the age of three years and/or weighting less than 15 Kg performed at the Hospital Clínico San Carlos between 1991 and 1999. Receptors were divided into two groups depending on the age at the time of transplantation; group I included patients younger than 50 years and group II patients older than 50.

RESULTS

We study 49 kidney transplants with pediatric donors (8.6%); 22 of them were included in group I and 27 in group II. There were no deaths among receptors younger than 50 years. Five-year survival for group II was 75.99%. Five-year graft survival what's 81.82% for group I, and 88.89% for group II (p 0.45).

CONCLUSIONS

Receptor's age does not seem to influence graft survival when this kind of organs are used; we consider that the lower incidence of acute rejection in patients older than 50 years may explain the excellent response.

摘要

目的

评估受体年龄对接受3岁以下和/或体重小于15千克供体器官的肾移植结果的影响。

方法

我们回顾性研究了1991年至1999年在圣卡洛斯临床医院进行的接受3岁以下和/或体重小于15千克供体器官的肾移植。根据移植时的年龄将受体分为两组;第一组包括年龄小于50岁的患者,第二组包括年龄大于50岁的患者。

结果

我们研究了49例接受小儿供体的肾移植(8.6%);其中22例属于第一组,27例属于第二组。年龄小于50岁的受体中无死亡病例。第二组的5年生存率为75.99%。第一组的5年移植物生存率为81.82%,第二组为88.89%(p=0.45)。

结论

使用这类器官时,受体年龄似乎不影响移植物存活;我们认为50岁以上患者急性排斥反应发生率较低可能解释了其良好的反应。

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Arch Esp Urol. 2003 Jun;56(5):491-5.
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