Liu Yongjian, Mou Shifen
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, PO Box 2871, Beijing 100085, China.
J Chromatogr A. 2003 May 16;997(1-2):225-35. doi: 10.1016/s0021-9673(03)00628-9.
Disinfection by products of haloacetic acids and perchlorate pose significant health risks, even at low microg/l levels in drinking water. A new method for the simultaneous determination of nine haloacetic acids (HAAs) and perchlorate as well as some common anions in one run with ion chromatography was developed. The HAAs tested included mono-, di-, trichloroacetic acids, mono, di-, tribromoacetic acids, bromochloroacetic acid, dibromochloroacetic acid, and bromodichloroacetic acid. Two high-capacity anion-exchange columns, a carbonate-selective column and a hydroxide-selective hydrophilic one, were used for the investigation. With the carbonate-selective column, the nine HAAs as well as fluoride, chloride, nitrite, nitrate, phosphate and sulfate could be well separated and determined in one run. With the very hydrophilic column and a gradient elution of sodium hydroxide, methanol and deionized water, the nine HAAs, fluoride, chloride, nitrite, nitrate as well as perchlorate could be simultaneously determined in one run within 34 min. The detection limits for HAAs were between 1.11 and 9.32 microg/l. For perchlorate, it was 0.60 microg/l.
即使饮用水中卤乙酸和高氯酸盐的消毒副产物含量低至微克/升水平，也会带来重大健康风险。开发了一种离子色谱法，可一次同时测定9种卤乙酸（HAA）、高氯酸盐以及一些常见阴离子。所检测的卤乙酸包括一氯乙酸、二氯乙酸、三氯乙酸、一溴乙酸、二溴乙酸、三溴乙酸、溴氯乙酸、二溴氯乙酸和溴二氯乙酸。使用了两根高容量阴离子交换柱，一根是碳酸盐选择性柱，另一根是氢氧化物选择性亲水柱进行研究。使用碳酸盐选择性柱时，9种卤乙酸以及氟化物、氯化物、亚硝酸盐、硝酸盐、磷酸盐和硫酸盐可在一次进样中得到良好分离和测定。使用非常亲水的柱子以及氢氧化钠、甲醇和去离子水的梯度洗脱，9种卤乙酸、氟化物、氯化物、亚硝酸盐、硝酸盐以及高氯酸盐可在34分钟内一次进样同时测定。卤乙酸的检测限在1.11至9.32微克/升之间。高氯酸盐的检测限为0.60微克/升。
